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Western Blot (WB) (Western blot analysis of CMTM6 expression in rat testis (A), CT26 (B), A549 (C), LO2 (D) whole cell lysates.)

Rabbit CMTM6 Polyclonal Antibody | anti-CMTM6 antibody

Anti-CMTM6 Antibody

Gene Names
CMTM6; CKLFSF6; PRO2219
Reactivity
Human, Mouse, Rat, Monkey
Applications
Western Blot
Purity
Purified by immunogen affinity chromatography.
Synonyms
CMTM6; Polyclonal Antibody; Anti-CMTM6 Antibody; CKLFSF6; CKLF-like MARVEL transmembrane domain-containing protein 6; Chemokine-like factor superfamily member 6; anti-CMTM6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of CMTM6 protein.
Purity/Purification
Purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
Sequence Length
183
Applicable Applications for anti-CMTM6 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CMTM6.
Preparation and Storage
Upon delivery aliquot and store at-20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of CMTM6 expression in rat testis (A), CT26 (B), A549 (C), LO2 (D) whole cell lysates.)

Western Blot (WB) (Western blot analysis of CMTM6 expression in rat testis (A), CT26 (B), A549 (C), LO2 (D) whole cell lysates.)
Related Product Information for anti-CMTM6 antibody
Rabbit polyclonal antibody to CMTM6

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
20,419 Da
NCBI Official Full Name
CKLF-like MARVEL transmembrane domain-containing protein 6
NCBI Official Synonym Full Names
CKLF like MARVEL transmembrane domain containing 6
NCBI Official Symbol
CMTM6
NCBI Official Synonym Symbols
CKLFSF6; PRO2219
NCBI Protein Information
CKLF-like MARVEL transmembrane domain-containing protein 6
UniProt Protein Name
CKLF-like MARVEL transmembrane domain-containing protein 6
UniProt Gene Name
CMTM6

NCBI Description

This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene is widely expressed in many tissues, but the exact function of the encoded protein is unknown. [provided by RefSeq, Jul 2008]

Uniprot Description

Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its STUB1-mediated ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately triggering T-cell anergy.

Research Articles on CMTM6

Similar Products

Product Notes

The CMTM6 cmtm6 (Catalog #AAA8303997) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CMTM6 Antibody reacts with Human, Mouse, Rat, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's CMTM6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the CMTM6 cmtm6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CMTM6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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