Rabbit anti-Human, Mouse CLTCL1 Polyclonal Antibody | anti-CLTCL1 antibody

CLTCL1 Rabbit Polyclonal

Cat. Num. AAA768011

• Gene Names: CLTCL1; CLTD; CHC22; CLH22; CLTCL
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunoprecipitation
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: CLTCL1; Polyclonal Antibody; CLTCL1 Rabbit Polyclonal; anti-CLTCL1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 1583

• Applicable Applications for anti-CLTCL1 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
• Immunogen: Clathrin, heavy chain-like 1
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis using MBS768011 (CLTCL1 antibody) at dilution of 1:50)

Testing Data

()

Western Blot (WB)

(Jurkat cells were subjected to SDS PAGE followed by western blot with MBS768011 (CLTCL1 antibody) at dilution of 1:800)

NCBI and Uniprot Product Information

• NCBI GI #: 242247001
• NCBI GeneID: 8218
• NCBI Accession #: NP_001826.3
• NCBI GenBank Nucleotide #: NM_001835.3
• Molecular Weight: 180,296 Da
• NCBI Official Full Name: clathrin heavy chain 2 isoform 2
• NCBI Official Synonym Full Names: clathrin heavy chain like 1
• NCBI Official Symbol: CLTCL1
• NCBI Official Synonym Symbols: CLTD; CHC22; CLH22; CLTCL
• NCBI Protein Information: clathrin heavy chain 2
• UniProt Protein Name: Clathrin heavy chain 2
• UniProt Gene Name: CLTCL1
• UniProt Synonym Gene Names: CLH22; CLTCL; CLTD; CLH-22
• UniProt Entry Name: CLH2_HUMAN

NCBI Description

This gene is a member of the clathrin heavy chain family and encodes a major protein of the polyhedral coat of coated pits and vesicles. Chromosomal aberrations involving this gene are associated with meningioma, DiGeorge syndrome, and velo-cardio-facial syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

Uniprot Description

CLTD: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. Belongs to the clathrin heavy chain family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: clathrin coat of trans-Golgi network vesicle; clathrin-coated vesicle; coated pit; cytosol; early endosome; late endosome; membrane; plasma membrane; recycling endosome; spindle; trans-Golgi network

Molecular Function: protein binding; signal transducer activity; structural molecule activity

Biological Process: anatomical structure morphogenesis; intracellular protein transport; mitosis; positive regulation of glucose import; receptor-mediated endocytosis; retrograde transport, endosome to Golgi; signal transduction