Mouse RKIP Monoclonal Antibody | anti-RKIP antibody

RKIP Antibody

Cat. Num. AAA852226

• Gene Names: PEBP1; PBP; HCNP; PEBP; RKIP; HCNPpp; PEBP-1; HEL-210; HEL-S-34; HEL-S-96
• Applications: ELISA, Western Blot
• Synonyms: RKIP; Monoclonal Antibody; RKIP Antibody; anti-RKIP antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2a
• Specificity: Anti-RKIP recognizes RKIP expression in SW480 whole cell lysate.
• Form/Format: Each vial contains 100 ug IgG in 100 ul of citrate-tris-HCl buffer pH7.0 with 0.02% Proclin 300.
• Sequence Length: 187

• Applicable Applications for anti-RKIP antibody: ELISA (EIA), Western Blot (WB-Ce)
• Immunogen: Recombinant protein corresponding to full length RKIP.
• Preparation and Storage: The antibody may be stored at-20 degree C for one year in its original formulation. Additionally, antibody may be stored at 2 degree C to 8 degree C for up to 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles of the diluted antibody.

Testing Data

Related Product Information for anti-RKIP antibody

Purified mouse monoclonal antibody generated using E Coli expressed recombinant protein RKIP as immunogen.

Product Categories/Family for anti-RKIP antibody

Plant antibody

NCBI and Uniprot Product Information

• NCBI GI #: 4505621
• NCBI GeneID: 5037
• NCBI Accession #: NP_002558.1
• NCBI GenBank Nucleotide #: NM_002567.2
• UniProt Accession #: P30086; B2R4S1
• Molecular Weight: 21,057 Da
• NCBI Official Full Name: phosphatidylethanolamine-binding protein 1
• NCBI Official Synonym Full Names: phosphatidylethanolamine binding protein 1
• NCBI Official Symbol: PEBP1
• NCBI Official Synonym Symbols: PBP; HCNP; PEBP; RKIP; HCNPpp; PEBP-1; HEL-210; HEL-S-34; HEL-S-96
• NCBI Protein Information: phosphatidylethanolamine-binding protein 1
• UniProt Protein Name: Phosphatidylethanolamine-binding protein 1
• UniProt Gene Name: PEBP1
• UniProt Synonym Gene Names: PBP; PEBP; PEBP-1; RKIP; HCNP

NCBI Description

This gene encodes a member of the phosphatidylethanolamine-binding family of proteins and has been shown to modulate multiple signaling pathways, including the MAP kinase (MAPK), NF-kappa B, and glycogen synthase kinase-3 (GSK-3) signaling pathways. The encoded protein can be further processed to form a smaller cleavage product, hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in neural development. This gene has been implicated in numerous human cancers and may act as a metastasis suppressor gene. Multiple pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Jul 2015]

Uniprot Description

Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation.