Immunohistochemistry (IHC)
(Anti-CLIC1/NCC27 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Goat CLIC1/NCC27 Polyclonal Antibody | anti-CLIC1/NCC27 antibody
Anti-CLIC1/NCC27 Antibody (aa71-82)
Gene Names
CLIC1; G6; CL1C1; NCC27
Reactivity
HumanPredicted: Rabbit, Mouse, Goat, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Monkey
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
CLIC1/NCC27; Polyclonal Antibody; Anti-CLIC1/NCC27 Antibody (aa71-82); Rabbit Polyclonal (IgG) to Human CLIC1/NCC27; CLIC1; Chloride channel ABP; G6; Nuclear chloride channel-27; p64CLCP; RNCC protein; HRNCC; NCC27; anti-CLIC1/NCC27 antibody
Host
Goat
Reactivity
Human
Predicted: Rabbit, Mouse, Goat, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Monkey
Predicted: Rabbit, Mouse, Goat, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Monkey
Clonality
Polyclonal
Specificity
Human CLIC1/NCC27.
Purity/Purification
Immunoaffinity Purified
Form/Format
Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Sequence Length
241
Applicable Applications for anti-CLIC1/NCC27 antibody
ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
ELISA: 1:32000
IHC-P: 5 ug/ml
WB: 1-3 ug/ml
IHC-P: 5 ug/ml
WB: 1-3 ug/ml
Immunogen
Synthetic peptide C-TEVHTDTNKIEE from an internal region of human CLIC1/NCC27 (NP_001279.2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Mouse, Rat, Ferret, Bovine, Bat, Goat, Elephant, Panda, Rabbit, Horse, Pig, Guinea pig, Platypus, Lizard (100%); Zebrafish (92%); Xenopus, Medaka, Pike, Catfish, Pufferfish (83%).
Conjugation
Unconjugated
Epitope
aa71-82
Preparation and Storage
Store at -20 degree C.
Avoid freeze-thaw cycles.
Avoid freeze-thaw cycles.
Immunohistochemistry (IHC)
(Anti-CLIC1/NCC27 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-CLIC1/NCC27 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Western Blot (WB)
(CLIC1 antibody EB12398 (2 ug/ml) staining of U937 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
(CLIC1 antibody EB12398 (2 ug/ml) staining of U937 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Related Product Information for anti-CLIC1/NCC27 antibody
Chloride channels are a diverse group of proteins that regulatefundamental cellular processes including stabilization of cell membranepotential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is amember of the p64 family; the protein localizes principally to the cellnucleus and exhibits both nuclear and plasma membrane chloride ionchannel activity.
Product Categories/Family for anti-CLIC1/NCC27 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26,923 Da
NCBI Official Full Name
chloride intracellular channel protein 1
NCBI Official Synonym Full Names
chloride intracellular channel 1
NCBI Official Symbol
CLIC1
NCBI Official Synonym Symbols
G6; CL1C1; NCC27
NCBI Protein Information
chloride intracellular channel protein 1
UniProt Protein Name
Chloride intracellular channel protein 1
UniProt Gene Name
CLIC1
UniProt Synonym Gene Names
G6; NCC27; NCC27; hRNCC
NCBI Description
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. [provided by RefSeq, Jul 2008]
Uniprot Description
Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.
Research Articles on CLIC1/NCC27
Similar Products
Product Notes
The CLIC1/NCC27 clic1 (Catalog #AAA2401035) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Anti-CLIC1/NCC27 Antibody (aa71-82) reacts with Human Predicted: Rabbit, Mouse, Goat, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's CLIC1/NCC27 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). ELISA: 1:32000 IHC-P: 5 ug/ml WB: 1-3 ug/ml. Researchers should empirically determine the suitability of the CLIC1/NCC27 clic1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLIC1/NCC27, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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