Rabbit anti-Human CLEC4D Polyclonal Antibody | anti-CLEC4D antibody

CLEC4D, ID (CLEC4D, CLECSF8, MCL, C-type lectin domain family 4 member D, C-type lectin superfamily member 8, C-type lectin-like receptor 6) (Azide free) (HRP)

Cat. Num. AAA6286694

• Gene Names: CLEC4D; MCL; MPCL; CLEC6; CLEC-6; CLECSF8; MGC40078
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CLEC4D; Polyclonal Antibody; ID (CLEC4D; CLECSF8; MCL; C-type lectin domain family 4 member D; C-type lectin superfamily member 8; C-type lectin-like receptor 6) (Azide free) (HRP); C-type lectin-like receptor 6; anti-CLEC4D antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

• Applicable Applications for anti-CLEC4D antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: CLEC4D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-153 amino acids from the Central region of human CLEC4D.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(CLEC4D Antibody (Center) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the CLEC4D antibody detected the CLEC4D protein (arrow).)

Related Product Information for anti-CLEC4D antibody

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Product Categories/Family for anti-CLEC4D antibody

Antibodies; Lectins

References

Flornes, L.M., et al. Immunogenetics 56(7):506-517(2004). Arce, I., et al. Eur. J. Immunol. 34(1):210-220(2004). Ebner, S., et al. Proteins 53(1):44-55(2003). Drickamer, K. Curr. Opin. Struct. Biol. 9(5):585-590(1999).

NCBI and Uniprot Product Information

• NCBI GI #: 31542313
• NCBI GeneID: 338339
• NCBI Accession #: NP_525126.2
• NCBI GenBank Nucleotide #: NM_080387.4
• UniProt Accession #: Q8WXI8; Q8N5J5
• Molecular Weight: 24,704 Da
• NCBI Official Full Name: C-type lectin domain family 4 member D
• NCBI Official Synonym Full Names: C-type lectin domain family 4, member D
• NCBI Official Symbol: CLEC4D
• NCBI Official Synonym Symbols: MCL; MPCL; CLEC6; CLEC-6; CLECSF8; MGC40078
• NCBI Protein Information: C-type lectin domain family 4 member D; OTTHUMP00000239173; OTTHUMP00000239174; C-type lectin receptor; macrophage C-type lectin; C-type lectin-like receptor 6; C-type lectin superfamily member 8; C-type (calcium dependent, carbohydrate-recognition domain
• UniProt Protein Name: C-type lectin domain family 4 member D
• Protein Family: C-type lectin domain family
• UniProt Gene Name: CLEC4D
• UniProt Synonym Gene Names: CLECSF8; MCL; CLEC-6
• UniProt Entry Name: CLC4D_HUMAN

NCBI Description

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq]

Uniprot Description

CLEC4D: Functions as an endocytic receptor. May be involved in antigen uptake at the site of infection, either for clearance of the antigen, or for processing and further presentation to T cells.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13.31

Cellular Component: integral to membrane

Molecular Function: carbohydrate binding

Biological Process: innate immune response