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Immunohistochemistry (IHC) (Anti-CLDN5 / Claudin 5 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.)

Rabbit anti-Human, Mouse CLDN5 / Claudin 5 Polyclonal Antibody | anti-CLDN5 antibody

Rabbit Polyclonal to Mouse CLDN5 / Claudin 5

Gene Names
CLDN5; AWAL; BEC1; TMVCF; CPETRL1
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
CLDN5 / Claudin 5; Polyclonal Antibody; Rabbit Polyclonal to Mouse CLDN5 / Claudin 5; Anti-CLDN5 / Claudin 5 Antibody (C-Terminus) IHC-plus; CLDN5; BEC1; AWAL; Claudin-5; CPETRL1; TMDVCF; TMVCF; Claudin 5; Mouse CLDN5; anti-CLDN5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Immunoaffinity Purified
Form/Format
10 mM PBS, pH 7.4, BSA, sodium azide.
Concentration
0.94 mg/ml (varies by lot)
Sequence Length
303
Applicable Applications for anti-CLDN5 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes
IHC-P (15 ug/ml), WB
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Target Species
Mouse
Immunogen Description
A synthetic peptide derived from the C-terminus of mouse Claudin-5.
Immunogen Type
Synthetic peptide
Immunogen
CLDN5 / Claudin 5 antibody was raised against a synthetic peptide derived from the C-terminus of mouse Claudin-5.
Antigen Modification
C-Terminus
Preparation and Storage
Store at 2 degree C to 8 degree C degrees. Do not freeze.

Immunohistochemistry (IHC)

(Anti-CLDN5 / Claudin 5 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.)

Immunohistochemistry (IHC) (Anti-CLDN5 / Claudin 5 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.)

Immunohistochemistry (IHC)

(Anti-CLDN5 / Claudin 5 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.)

Immunohistochemistry (IHC) (Anti-CLDN5 / Claudin 5 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.)
Related Product Information for anti-CLDN5 antibody
This gene is deleted in patients with velocardiofacial syndrome which is characterized by a wide spectrum of phenotypes including cleft palate, conotruncal heart defects, and facial dysmorphology. It is expressed abundantly in human adult lung, heart, and skeletal muscle.
Product Categories/Family for anti-CLDN5 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23,147 Da
NCBI Official Full Name
claudin-5
NCBI Official Synonym Full Names
claudin 5
NCBI Official Symbol
CLDN5
NCBI Official Synonym Symbols
AWAL; BEC1; TMVCF; CPETRL1
NCBI Protein Information
claudin-5; TMDVCF; transmembrane protein deleted in VCFS; transmembrane protein deleted in velocardiofacial syndrome
UniProt Protein Name
Claudin-5
Protein Family
UniProt Gene Name
CLDN5
UniProt Synonym Gene Names
AWAL; TMVCF; TMDVCF
UniProt Entry Name
CLD5_HUMAN

NCBI Description

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2008]

Uniprot Description

Claudin-5: Plays a major role in tight junction-specific obliteration of the intercellular space. Belongs to the claudin family.

Protein type: Cytoskeletal; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: tight junction; integral to membrane; plasma membrane; intercellular junction

Molecular Function: identical protein binding; structural molecule activity

Biological Process: calcium-independent cell-cell adhesion

Research Articles on CLDN5

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Product Notes

The CLDN5 cldn5 (Catalog #AAA242654) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Mouse CLDN5 / Claudin 5 reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CLDN5 / Claudin 5 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB). IHC-P (15 ug/ml), WB Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the CLDN5 cldn5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLDN5 / Claudin 5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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