Western Blot (WB)
(Western Blot analysis in HepG2 cell line lysates (35ug/lane) usingMBS648745. This demonstrates that MBS648745 detected the HDGR2 protein (arrow).)
Rabbit anti-Human HDGR2 Polyclonal Antibody | anti-HDGR2 antibody
HDGR2, NT (HDGFRP2, HDGF2, Hepatoma-derived growth factor-related protein 2, Hepatoma-derived growth factor 2) (Azide free) (HRP)
Gene Names
HDGFL2; HRP2; HDGF2; HRP-2; HDGF-2; HDGFRP2
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Protein A and Peptide Affinity Chromatography.
Synonyms
HDGR2; Polyclonal Antibody; NT (HDGFRP2; HDGF2; Hepatoma-derived growth factor-related protein 2; Hepatoma-derived growth factor 2) (Azide free) (HRP); HDGFRP2; Hepatoma-derived growth factor 2; anti-HDGR2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human HDGR2.
Purity/Purification
Purified by Protein A and Peptide Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
Applicable Applications for anti-HDGR2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 51-79 in the N-terminal region of human HDGR2, UniProt Accession #Q7Z4V5. Species sequence homology: chicken, mouse, rat, Xenopus
Conjugate
HRP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis in HepG2 cell line lysates (35ug/lane) usingMBS648745. This demonstrates that MBS648745 detected the HDGR2 protein (arrow).)
Western Blot (WB)
(Western Blot analysis in HepG2 cell line lysates (35ug/lane) usingMBS648745. This demonstrates that MBS648745 detected the HDGR2 protein (arrow).)
Related Product Information for anti-HDGR2 antibody
This gene encodes a member of the hepatoma-derived growth factor (HDGF) family. Two alternatively spliced transcript variants encoding slightly different isoforms have been found for this gene.
Product Categories/Family for anti-HDGR2 antibody
References
1. Matsuoka, S., et al. Science 316(5828):1160-1166(2007). 2. Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007). 3. Olsen, J.V., et al. Cell 127(3):635-648(2006). 4. Vandegraaff, N., et al. Virology 346(2):415-426(2006). 5. Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
74,729 Da
NCBI Official Full Name
hepatoma-derived growth factor-related protein 2 isoform 1
NCBI Official Synonym Full Names
HDGF like 2
NCBI Official Symbol
HDGFL2
NCBI Official Synonym Symbols
HRP2; HDGF2; HRP-2; HDGF-2; HDGFRP2
NCBI Protein Information
hepatoma-derived growth factor-related protein 2
UniProt Protein Name
Hepatoma-derived growth factor-related protein 2
UniProt Gene Name
HDGFRP2
UniProt Synonym Gene Names
HDGF2; HRP-2; HDGF-2
UniProt Entry Name
HDGR2_HUMAN
NCBI Description
This gene encodes a member of the hepatoma-derived growth factor (HDGF) family. The protein includes an N-terminal PWWP domain that binds to methyl-lysine-containing histones, with specific binding of this protein to tri-methylated lysines 36 and 79 of histone H3, and di- and tri-methylated lysine 20 of histone H4. The protein functions in LEDGF/p75-independent HIV-1 replication by determining HIV-1 integration site selection. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Uniprot Description
HDGF2: a member of the hepatoma-derived growth factor (HDGF) family. Two alternatively spliced transcript variants encoding slightly different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: nucleoplasm; mitochondrion; nucleus
Molecular Function: DNA binding; chromatin binding
Biological Process: transcription, DNA-dependent
Research Articles on HDGR2
Similar Products
Product Notes
The HDGR2 hdgfrp2 (Catalog #AAA6305992) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HDGR2, NT (HDGFRP2, HDGF2, Hepatoma-derived growth factor-related protein 2, Hepatoma-derived growth factor 2) (Azide free) (HRP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HDGR2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the HDGR2 hdgfrp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HDGR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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