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Western Blot (WB) (Western Blot analysis of HUVEC and 293T cell, Mouse bladder, Human placenta and Mouse kidney tissue using CLDN23 Polyclonal Antibody at dilution of 1:200)

Rabbit CLDN23 Polyclonal Antibody | anti-CLDN23 antibody

CLDN23 Polyclonal Antibody

Gene Names
CLDN23; CLDNL; hCG1646163
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Antigen affinity purification
Synonyms
CLDN23; Polyclonal Antibody; CLDN23 Polyclonal Antibody; CLDNL; hCG1646163; anti-CLDN23 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1.6mg/mL (varies by lot)
Sequence Length
292
Applicable Applications for anti-CLDN23 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant protein of human CLDN23
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Western Blot (WB)

(Western Blot analysis of HUVEC and 293T cell, Mouse bladder, Human placenta and Mouse kidney tissue using CLDN23 Polyclonal Antibody at dilution of 1:200)

Western Blot (WB) (Western Blot analysis of HUVEC and 293T cell, Mouse bladder, Human placenta and Mouse kidney tissue using CLDN23 Polyclonal Antibody at dilution of 1:200)
Related Product Information for anti-CLDN23 antibody
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in germinal center B-cells, placenta and stomach as well as in colon tumor. This gene is down-regulated in intestinal type gastric cancer.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
31,915 Da
NCBI Official Full Name
claudin-23
NCBI Official Synonym Full Names
claudin 23
NCBI Official Symbol
CLDN23
NCBI Official Synonym Symbols
CLDNL; hCG1646163
NCBI Protein Information
claudin-23; 2310014B08Rik
UniProt Protein Name
Claudin-23
Protein Family
UniProt Gene Name
CLDN23
UniProt Entry Name
CLD23_HUMAN

NCBI Description

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in germinal center B-cells, placenta and stomach as well as in colon tumor. This gene is down-regulated in intestinal type gastric cancer. [provided by RefSeq, Aug 2010]

Uniprot Description

Claudin-23: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Belongs to the claudin family.

Protein type: Cell adhesion; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 8p23.1

Cellular Component: tight junction; integral to membrane; plasma membrane

Molecular Function: identical protein binding; structural molecule activity

Biological Process: intercellular junction assembly and maintenance; calcium-independent cell-cell adhesion

Research Articles on CLDN23

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Product Notes

The CLDN23 cldn23 (Catalog #AAA2520249) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CLDN23 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CLDN23 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the CLDN23 cldn23 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLDN23, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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