Western Blot (WB)
(Western Blot (WB) analysis of CLCC1 (D429) pAb at 1:500 dilutionLane1:SGC7901 whole cell lysate (40ug) Lane2:HCT116 whole cell lysate (40ug) Lane3:H1792 whole cell lysate (20ug))
Rabbit anti-Human CLCC1 Polyclonal Antibody | anti-CLCC1 antibody
CLCC1 (D429) Polyclonal Antibody
Reactivity
Human
Applications
Immunohistochemistry
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
CLCC1; Polyclonal Antibody; CLCC1 (D429) Polyclonal Antibody; Chloride channel CLIC-like protein 1; Mid-1-related chloride channel protein 1; KIAA0761; MCLC; anti-CLCC1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
CLCC1 (D429) polyclonal antibody detects endogenous levels of CLCC1 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
551
Applicable Applications for anti-CLCC1 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:200
Immunogen
Synthetic peptide, corresponding to amino acids 396-445 of Human CLCC1.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of CLCC1 (D429) pAb at 1:500 dilutionLane1:SGC7901 whole cell lysate (40ug) Lane2:HCT116 whole cell lysate (40ug) Lane3:H1792 whole cell lysate (20ug))
Western Blot (WB)
(Western Blot (WB) analysis of CLCC1 (D429) pAb at 1:500 dilutionLane1:SGC7901 whole cell lysate (40ug) Lane2:HCT116 whole cell lysate (40ug) Lane3:H1792 whole cell lysate (20ug))
Related Product Information for anti-CLCC1 antibody
Chloride channels (CLCs) regulate cellular traffic of chloride ions, a critical component of all living cells. CLCs are involved in membrane potential stabilization, signal transduction, cell volume regulation and organic solute transport. CLCC1 (Chloride channel CLIC-like protein 1), also known as MCLC (Mid-1-related chloride channel) or KIAA0761, is a 551 amino acid multi-pass membrane protein that belongs to the chloride channel MCLC family. CLCC1 is related to the Saccharomyces cerevisiaeprotein Mid-1 and is believed to function as an intracellular chloride channel that is expressed in lung, brain, muscle, liver and testis. Localizing to intracellular compartments such as the Golgi apparatus, the endoplasmic reticulum (ER) and the nuclear envelope, CLCC1 is expressed as four isoforms due to alternative splicing events, namely hMCLC-1, hMCLC-2, hMCLC-3 and hMCLC-4.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 62kDa
NCBI Official Full Name
chloride channel CLIC-like protein 1 isoform 1
UniProt Protein Name
Chloride channel CLIC-like protein 1
Protein Family
UniProt Gene Name
CLCC1
UniProt Synonym Gene Names
KIAA0761; MCLC
UniProt Entry Name
CLCC1_HUMAN
Uniprot Description
CLCC1: Seems to act as a chloride ion channel. Belongs to the chloride channel MCLC family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Endoplasmic reticulum; Channel, chloride; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p13.3
Cellular Component: Golgi apparatus; membrane; intracellular membrane-bound organelle; endoplasmic reticulum; nucleus
Molecular Function: chloride channel activity
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Product Notes
The CLCC1 clcc1 (Catalog #AAA3003595) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CLCC1 (D429) Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CLCC1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-1:200. Researchers should empirically determine the suitability of the CLCC1 clcc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLCC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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