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Western Blot (WB) (CLCA3P Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the CLCA3P antibody detected the CLCA3P protein (arrow).)

Rabbit anti-Human CLCA3P Polyclonal Antibody

CLCA3P, ID (CLCA3P, CLCA3, Calcium-activated chloride channel regulator family member 3)

Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
CLCA3P; Polyclonal Antibody; ID (CLCA3P; CLCA3; Calcium-activated chloride channel regulator family member 3); Anti -CLCA3P; anti-CLCA3P antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Applicable Applications for anti-CLCA3P antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunogen
CLCA3P antibody is generated from rabbits immunized with a KLH conjugated synthetic between 69-98 amino acids selected from the Central region of human CLCA3P.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(CLCA3P Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the CLCA3P antibody detected the CLCA3P protein (arrow).)

Western Blot (WB) (CLCA3P Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the CLCA3P antibody detected the CLCA3P protein (arrow).)
Related Product Information for anti-CLCA3P antibody
mCLCA3 (alias gob-5) is the third murine member of the family of calcium-activated chloride channels (CLCA-family). mCLCA3 plays a role in diseases with secretory dysfunctions, including asthma and cystic fibrosis. The mCLCA3 protein is located in mucin granule membranes of goblet cells of the intestinal, respiratory and reproductive tracts. It is also secreted into the mucin layer on mucosal membranes. The protein appears to be involved in the synthesis, condensation or secretion of mucins.
Product Categories/Family for anti-CLCA3P antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI Official Full Name
Calcium-activated chloride channel regulator family member 3

NCBI Description

This gene is a transcribed pseudogene belonging to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. This gene contains several nonsense codons compared to other family members that render the transcript a candidate for nonsense-mediated mRNA decay (NMD). Therefore, this gene is unlikely to be protein-coding. [provided by RefSeq, Jan 2009]

Uniprot Description

CLCA3: a transcribed pseudogene belonging to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. This gene contains several nonsense codons compared to other family members that render the transcript a candidate for nonsense-mediated mRNA decay (NMD). Therefore, unlikely to be protein-coding. [provided by RefSeq, Jan 2009]

Protein type: Secreted; Channel, ligand-gated; Secreted, signal peptide; Channel, chloride

Chromosomal Location of Human Ortholog: 1p22.3

Cellular Component: extracellular space; extracellular region; plasma membrane

Molecular Function: chloride channel activity; transporter activity; calcium channel activity; voltage-gated ion channel activity

Biological Process: transport; transmembrane transport

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Product Notes

The CLCA3P (Catalog #AAA6001478) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CLCA3P, ID (CLCA3P, CLCA3, Calcium-activated chloride channel regulator family member 3) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CLCA3P can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the CLCA3P for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLCA3P, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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