Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human brain tissue using Claudin 5 antibody.)
Rabbit anti-Human Claudin 5 Polyclonal Antibody | anti-CLDN5 antibody
Claudin 5 Antibody
Immunohistochemistry: 1:50~1:100
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human brain tissue using Claudin 5 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human brain tissue using Claudin 5 antibody.)
Western Blot (WB)
(Western blot analysis of extracts from A549 cells, using Claudin 5 antibody.)
Western Blot (WB)
(Western blot analysis of extracts from A549 cells, using Claudin 5 antibody.)
Western Blot (WB)
(Western blot analysis of extracts from 293 cells (Lane 2), K562 cells (Lane 3) and 3T3 cells (Lane 4), using Claudin 5 antiobdy. The lane on the left is treated with synthesized peptide.)
Western Blot (WB)
(Western blot analysis of extracts from 293 cells (Lane 2), K562 cells (Lane 3) and 3T3 cells (Lane 4), using Claudin 5 antiobdy. The lane on the left is treated with synthesized peptide.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2008]
Uniprot Description
Claudin-5: Plays a major role in tight junction-specific obliteration of the intercellular space. Belongs to the claudin family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Cytoskeletal
Chromosomal Location of Human Ortholog: 22q11.21
Cellular Component: apicolateral plasma membrane; cortical actin cytoskeleton; integral to membrane; intercellular junction; tight junction
Molecular Function: identical protein binding; structural molecule activity
Biological Process: calcium-independent cell-cell adhesion; intercellular junction assembly; learning; palate development; transforming growth factor beta receptor signaling pathway
Research Articles on CLDN5
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Product Notes
The CLDN5 cldn5 (Catalog #AAA9409612) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Claudin 5 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Claudin 5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:500~1:3000 Immunohistochemistry: 1:50~1:100. Researchers should empirically determine the suitability of the CLDN5 cldn5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Claudin 5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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