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Western Blot (WB) (Western blot analysis of Claudin 5 expression in human fetal brain lysate.)

Rabbit anti-Human Claudin 5 Polyclonal Antibody | anti-CLDN5 antibody

Anti-Claudin 5 Rabbit pAb

Gene Names
CLDN5; AWAL; BEC1; TMVCF; TMDVCF; CPETRL1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Chromatography
Synonyms
Claudin 5; Polyclonal Antibody; Anti-Claudin 5 Rabbit pAb; Claudin5; Transmembrane protein deleted in VCFS; BEC1; CPETRL1; TMDVCF; AWAL; TMVCF; anti-CLDN5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Claudin 5 Antibody detects endogenous levels of total Claudin 5
Purity/Purification
Affinity Chromatography
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
303
Applicable Applications for anti-CLDN5 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
Immunogen
A synthesized peptide derived from human Claudin 5
Subcellular Location
Cell membrane; Multi-pass membrane protein
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.

Western Blot (WB)

(Western blot analysis of Claudin 5 expression in human fetal brain lysate.)

Western Blot (WB) (Western blot analysis of Claudin 5 expression in human fetal brain lysate.)
Related Product Information for anti-CLDN5 antibody
Plays a major role in tight junction-specific obliteration of the intercellular space.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
20kDa
NCBI Official Full Name
claudin-5 isoform 1
NCBI Official Synonym Full Names
claudin 5
NCBI Official Symbol
CLDN5
NCBI Official Synonym Symbols
AWAL; BEC1; TMVCF; TMDVCF; CPETRL1
NCBI Protein Information
claudin-5
UniProt Protein Name
Claudin-5
Protein Family
UniProt Gene Name
CLDN5
UniProt Synonym Gene Names
AWAL; TMVCF; TMDVCF

NCBI Description

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2018]

Uniprot Description

Plays a major role in tight junction-specific obliteration of the intercellular space.

Research Articles on CLDN5

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Product Notes

The CLDN5 cldn5 (Catalog #AAA4750829) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Claudin 5 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Claudin 5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the CLDN5 cldn5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Claudin 5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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