Rabbit anti-Human CKAP2 Polyclonal Antibody | anti-CKAP2 antibody
CKAP2 Antibody
Gene Names
CKAP2; LB1; TMAP; se20-10
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
CKAP2; Polyclonal Antibody; CKAP2 Antibody; AI461656; AW228814; CKAP 2; Ckap2; CKAP2_HUMAN; CTCL tumor antigen se20 10; CTCL tumor antigen se20-10; Cytoskeleton associated protein 2; Cytoskeleton-associated protein 2; DKFZp686L1238; FLJ10749; LB1; se20 10; TMAP; Tumor and microtubule associated protein; Tumor associated microtubule associated protein; Tumor- and microtubule-associated protein; anti-CKAP2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
CKAP2 Antibody detects endogenous levels of CKAP2.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-CKAP2 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human CKAP2.
Conjugation
Unconjugated
Similarity
Belongs to the CKAP2 family.
Subunit Structure
Associates with alpha- and beta-tubulins.
Tissue Specificity
Abundant in testis, thymus, and in tumor derived cell lines, while barely detectable in liver, prostate, and kidney.
Function
Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53-dependent manner (By similarity).
Note
Contrary to the ectopically expressed protein, endogenous CKAP2 does not colocalize with microtubules in G1, S and early G2. At late G2 and prophase after separation of duplicated centrosomes, colocalizes with gamma-tubulin and centrosome-proximal microtubules. From prometaphase through anaphase B, colocalizes with mitotic spindle poles and spindle microtubules. During cytokinesis, absent from midbody microtubules.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-CKAP2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
76,900 Da
NCBI Official Full Name
cytoskeleton-associated protein 2 isoform 2
NCBI Official Synonym Full Names
cytoskeleton associated protein 2
NCBI Official Symbol
CKAP2
NCBI Official Synonym Symbols
LB1; TMAP; se20-10
NCBI Protein Information
cytoskeleton-associated protein 2
UniProt Protein Name
Cytoskeleton-associated protein 2
Protein Family
UniProt Gene Name
CKAP2
UniProt Synonym Gene Names
LB1; TMAP
UniProt Entry Name
CKAP2_HUMAN
NCBI Description
This gene encodes a cytoskeleton-associated protein that stabalizes microtubules and plays a role in the regulation of cell division. The encoded protein is itself regulated through phosphorylation at multiple serine and threonine residues. There is a pseudogene of this gene on chromosome 14. Alternative splicing results in multiple transcript variations. [provided by RefSeq, Nov 2013]
Research Articles on CKAP2
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Product Notes
The CKAP2 ckap2 (Catalog #AAA9630731) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CKAP2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CKAP2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the CKAP2 ckap2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CKAP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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