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Western Blot (WB) (WB Suggested Anti-CIP29 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate)

Rabbit CIP29 Polyclonal Antibody | anti-SARNP antibody

CIP29 antibody - C-terminal region

Gene Names
SARNP; HCC1; THO1; CIP29; HSPC316
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Applications
Western Blot
Purity
Affinity Purified
Synonyms
CIP29; Polyclonal Antibody; CIP29 antibody - C-terminal region; anti-SARNP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence
Synthetic peptide located within the following region: VSSISRKSEDDEKLKKRKERFGIVTSSAGTGTTEDTEAKKRKRAERFGIA
Sequence Length
210
Applicable Applications for anti-SARNP antibody
Western Blot (WB)
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 83%; Zebrafish: 83%
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CIP29
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(WB Suggested Anti-CIP29 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate)

Western Blot (WB) (WB Suggested Anti-CIP29 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate)
Related Product Information for anti-SARNP antibody
This is a rabbit polyclonal antibody against CIP29. It was validated on Western Blot using a cell lysate as a positive control.

Target Description: CIP29 physically and functionally associates with DDX39, suggesting their cooperation in the RNA metabolism. CIP29 appears to be a new cytokine regulated protein involved in normal and cancer cell proliferation.
Product Categories/Family for anti-SARNP antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24kDa
NCBI Official Full Name
SAP domain-containing ribonucleoprotein
NCBI Official Synonym Full Names
SAP domain containing ribonucleoprotein
NCBI Official Symbol
SARNP
NCBI Official Synonym Symbols
HCC1; THO1; CIP29; HSPC316
NCBI Protein Information
SAP domain-containing ribonucleoprotein
UniProt Protein Name
SAP domain-containing ribonucleoprotein
UniProt Gene Name
SARNP
UniProt Synonym Gene Names
HCC1
UniProt Entry Name
SARNP_HUMAN

NCBI Description

This gene encodes a protein that is upregulated in response to various cytokines. The encoded protein may play a role in cell cycle progression. A translocation between this gene and the myeloid/lymphoid leukemia gene, resulting in expression of a chimeric protein, has been associated with acute myelomonocytic leukemia. Pseudogenes exist on chromosomes 7 and 8. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]

Uniprot Description

CIP29: Binds both single-stranded and double-stranded DNA with higher affinity for the single-stranded form. Specifically binds to scaffold/matrix attachment region DNA. Also binds single- stranded RNA. Enhances RNA unwinding activity of DDX39A. May participate in important transcriptional or translational control of cell growth, metabolism and carcinogenesis.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 12q13.2

Cellular Component: nucleoplasm; intracellular membrane-bound organelle; nuclear speck; nucleus

Molecular Function: DNA binding

Biological Process: regulation of translation; mRNA export from nucleus; regulation of transcription, DNA-dependent; transcription, DNA-dependent

Research Articles on SARNP

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Product Notes

The SARNP sarnp (Catalog #AAA3210068) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CIP29 antibody - C-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's CIP29 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the SARNP sarnp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: VSSISRKSED DEKLKKRKER FGIVTSSAGT GTTEDTEAKK RKRAERFGIA. It is sometimes possible for the material contained within the vial of "CIP29, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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