Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human thyroid tissue using MBS1493902 at dilution of 1:100)
Rabbit anti-Human CIART Polyclonal Antibody | anti-CIART antibody
CIART Antibody
Gene Names
CIART; GM129; CHRONO; C1orf51
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
>95%, Protein G Purified
Synonyms
CIART; Polyclonal Antibody; CIART Antibody; Circadian-associated transcriptional repressor; C1orf51; ChIP-derived repressor of network oscillator; Chrono; Computationally highlighted repressor of the network oscillator; anti-CIART antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G Purified
Sequence Length
385
Applicable Applications for anti-CIART antibody
ELISA (EIA), Immunohistochemistry (IHC)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Circadian-associated transcriptional repressor protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-139576 / sc-139575
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human thyroid tissue using MBS1493902 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human thyroid tissue using MBS1493902 at dilution of 1:100)
Related Product Information for anti-CIART antibody
Transcriptional repressor which forms a negative regulatory component of the circadian clock and acts independently of the circadian transcriptional repressors: CRY1, CRY2 and BHLHE41. In a histone deacetylase-dependent manner represses the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Abrogates the interaction of ARNTL/BMAL1 with the transcriptional coactivator CREBBP and can repress the histone acetyl-transferase activity of the CLOCK-ARNTL/BMAL1 heterodimer, reducing histone acetylation of its target genes. Rhythmically binds the E-box elements (5'-CACGTG-3') on circadian gene promoters and its occupancy shows circadian oscillation antiphasic to ARNTL/BMAL1. Interacts with the glucocorticoid receptor (NR3C1) and contributes to the repressive function in the glucocorticoid response (By similarity).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
12,982 Da
NCBI Official Full Name
circadian-associated transcriptional repressor isoform a
NCBI Official Synonym Full Names
circadian associated repressor of transcription
NCBI Official Symbol
CIART
NCBI Official Synonym Symbols
GM129; CHRONO; C1orf51
NCBI Protein Information
circadian-associated transcriptional repressor
UniProt Protein Name
Circadian-associated transcriptional repressor
Protein Family
UniProt Gene Name
CIART
UniProt Synonym Gene Names
C1orf51; Chrono
UniProt Entry Name
CIART_HUMAN
Uniprot Description
CHRONO: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 1q21.2
Cellular Component: nucleus; PML body
Molecular Function: protein binding
Biological Process: circadian regulation of gene expression; locomotor rhythm; negative regulation of transcription, DNA-dependent; transcription, DNA-dependent
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Product Notes
The CIART ciart (Catalog #AAA1493902) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CIART Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CIART can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the CIART ciart for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CIART, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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