Western Blot (WB)
(Western blotAll lanes: CBX8 antibody at 2ug/ml+jurkat whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 43kDaObserved band size: 43kDa)
Rabbit anti-Human Chromobox protein homolog 8 Polyclonal Antibody | anti-CBX8 antibody
Rabbit anti-human Chromobox protein homolog 8 polyclonal Antibody(CBX8)
IHC:1:20-1:200
Western Blot (WB)
(Western blotAll lanes: CBX8 antibody at 2ug/ml+jurkat whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 43kDaObserved band size: 43kDa)
Western Blot (WB)
(Western blotAll lanes: CBX8 antibody at 2ug/ml+jurkat whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 43kDaObserved band size: 43kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human skin using MBS1497218 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human skin using MBS1497218 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon cancer using MBS1497218at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon cancer using MBS1497218at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver cancer using MBS1497218 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver cancer using MBS1497218 at dilution 1:100)
NCBI and Uniprot Product Information
Uniprot Description
CBX8: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Protein type: Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 17q25.3
Cellular Component: heterochromatin; nuclear chromatin; nucleoplasm; nucleus; PcG protein complex
Molecular Function: methylated histone residue binding; protein binding; single-stranded RNA binding
Biological Process: cellular protein metabolic process; histone ubiquitination; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell proliferation; positive regulation of collagen biosynthetic process; positive regulation of DNA repair; post-translational protein modification; protein sumoylation; regulation of catalytic activity; transcription, DNA-dependent
Research Articles on CBX8
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Product Notes
The CBX8 cbx8 (Catalog #AAA1497218) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Chromobox protein homolog 8 polyclonal Antibody(CBX8) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Chromobox protein homolog 8 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Recommended dilution: WB:1:200-1000 IHC:1:20-1:200. Researchers should empirically determine the suitability of the CBX8 cbx8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Chromobox protein homolog 8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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