Western Blot (WB)
(Host: RabbitTarget Name: CHRFAM7ASample Tissue: Human MCF7Antibody Dilution: 1.0ug/ml)
Rabbit CHRFAM7A Polyclonal Antibody | anti-CHRFAM7A antibody
CHRFAM7A antibody - N-terminal region
Western Blot (WB)
(Host: RabbitTarget Name: CHRFAM7ASample Tissue: Human MCF7Antibody Dilution: 1.0ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: CHRFAM7ASample Tissue: Human MCF7Antibody Dilution: 1.0ug/ml)
Western Blot (WB)
(WB Suggested Anti-CHRFAM7A Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysateCHRFAM7A is supported by BioGPS gene expression data to be expressed in Jurkat)
Western Blot (WB)
(WB Suggested Anti-CHRFAM7A Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysateCHRFAM7A is supported by BioGPS gene expression data to be expressed in Jurkat)
Target Description: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7 is located on chromosome 15 in a region associated with several neuropsychiatric disorders. CHRFAM7A is is a hybrid between CHRNA7 and FAM7A.
NCBI and Uniprot Product Information
NCBI Description
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq, Jul 2008]
Uniprot Description
CHRFAM7A: Belongs to the ligand-gated ion channel (TC 1.A.9) family
Protein type: Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 15q13.1
Cellular Component: integral to membrane
Molecular Function: extracellular ligand-gated ion channel activity
Research Articles on CHRFAM7A
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Product Notes
The CHRFAM7A chrfam7a (Catalog #AAA3202570) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CHRFAM7A antibody - N-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's CHRFAM7A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the CHRFAM7A chrfam7a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: QFQLLIQHLW IAANCDIADE RFDATFHTNV LVNSSGHCQY LPPGIFKSSC. It is sometimes possible for the material contained within the vial of "CHRFAM7A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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