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Western Blot (WB) (Western Blot analysis of Jurkat cells using CHI3L1 Polyclonal Antibody at dilution of 1:5000)

Rabbit CHI3L1 Polyclonal Antibody | anti-CHI3L1 antibody

CHI3L1 Polyclonal Antibody

Gene Names
Chil1; Gp39; Brp39; Chi3l1; AW208766
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
CHI3L1; Polyclonal Antibody; CHI3L1 Polyclonal Antibody; 39 kDa synovial protein; ASRT7; Cartilage glycoprotein 39; CGP39; chitinase 3 like 1; Chitinase 3 like protein 1 precursor; chitinase; Chondrocyte protein YKL40; GP39; HCGP 3P; HCgp39; YKL40; anti-CHI3L1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-CHI3L1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:3000-1:6000
IHC: 1:200-1:500
Immunogen
Recombinant Mouse Chitinase-3-like protein 1 protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western Blot analysis of Jurkat cells using CHI3L1 Polyclonal Antibody at dilution of 1:5000)

Western Blot (WB) (Western Blot analysis of Jurkat cells using CHI3L1 Polyclonal Antibody at dilution of 1:5000)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver using CHI3L1 Polycloanl Antibody at dilution of 1:300)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver using CHI3L1 Polycloanl Antibody at dilution of 1:300)

Immunohistochemsitry (IHC)]

(Immunohistochemistry of paraffin-embedded Human breast cancer using CHI3L1 Polycloanl Antibody at dilution of 1:300)

Immunohistochemsitry (IHC)] (Immunohistochemistry of paraffin-embedded Human breast cancer using CHI3L1 Polycloanl Antibody at dilution of 1:300)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Mouse spleen using CHI3L1 Polycloanl Antibody at dilution of 1:300)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Mouse spleen using CHI3L1 Polycloanl Antibody at dilution of 1:300)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Rat lung using CHI3L1 Polycloanl Antibody at dilution of 1:300)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Rat lung using CHI3L1 Polycloanl Antibody at dilution of 1:300)
Related Product Information for anti-CHI3L1 antibody
Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.
Product Categories/Family for anti-CHI3L1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
42,805 Da
NCBI Official Full Name
Chitinase-3-like protein 1
NCBI Official Synonym Full Names
chitinase-like 1
NCBI Official Symbol
Chil1
NCBI Official Synonym Symbols
Gp39; Brp39; Chi3l1; AW208766
NCBI Protein Information
chitinase-3-like protein 1; GP-39; CGP-39; chitinase 3-like 1; cartilage glycoprotein 39; breast regression protein 39
UniProt Protein Name
Chitinase-3-like protein 1
Protein Family
UniProt Gene Name
Chi3l1
UniProt Synonym Gene Names
Brp39; Chil1; CGP-39; GP-39
UniProt Entry Name
CH3L1_MOUSE

Uniprot Description

CHI3L1: Carbohydrate-binding lectin with a preference for chitin. May play a role in defense against pathogens, or in tissue remodeling. May play an important role in the capacity of cells to respond to and cope with changes in their environment. A genetic variation in CHI3L1 is associated with susceptibility to asthma-related traits type 7 (ASRT7). Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing and dyspnea, bronchial hyperresponsiveness (BHR) as assessed by methacholine challenge test, serum IgE levels, atopy, and atopic dermatitis. Belongs to the glycosyl hydrolase 18 family.

Protein type: Secreted; Secreted, signal peptide; Cell adhesion

Cellular Component: extracellular space; endoplasmic reticulum; cytoplasm; extracellular region

Molecular Function: chitin binding; chitinase activity; hydrolase activity, hydrolyzing O-glycosyl compounds

Biological Process: positive regulation of protein kinase B signaling cascade; positive regulation of angiogenesis; apoptosis; carbohydrate metabolic process; activation of NF-kappaB-inducing kinase; immune response; chitin catabolic process; inflammatory response; lung development

Research Articles on CHI3L1

Similar Products

Product Notes

The CHI3L1 chi3l1 (Catalog #AAA2568147) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CHI3L1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CHI3L1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:3000-1:6000 IHC: 1:200-1:500. Researchers should empirically determine the suitability of the CHI3L1 chi3l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CHI3L1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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