<
Western Blot (WB)
(Western blot analysis of CHADL in mouse kidney tissue lysate with CHADL antibody at (A) 1 and (B) 2 μg/ml.)
Rabbit CHADL Polyclonal Antibody | anti-CHADL antibody
CHADL Antibody
Gene Names
CHADL; SLRR4B
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column.
Synonyms
CHADL; Polyclonal Antibody; CHADL Antibody; Chondoadherin-like protein; SLRR4B; anti-CHADL antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
CHADL antibody is human, mouse and rat reactive. CHADL antibody is predicted to not cross-react with Chondroadherin protein.
Purity/Purification
Affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
762
Applicable Applications for anti-CHADL antibody
ELISA (EIA), Western Blot (WB)
Application Notes
CHADL antibody can be used for the detection of CHADL by Western blot at 1 - 2 mug/mL.
Immunogen
CHADL antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human CHADL.
Buffer
Supplied in PBS containing 0.02% sodium azide.
Positive Control 1
Rat Skeletal Muscle Tissue Lysate
Conjugate
Unconjugated
Preparation and Storage
Store at 4 degree C for three months and -20 degree C, stable for up to one year.
Western Blot (WB)
(Western blot analysis of CHADL in mouse kidney tissue lysate with CHADL antibody at (A) 1 and (B) 2 μg/ml.)
Western Blot (WB)
(Western blot analysis of CHADL in mouse kidney tissue lysate with CHADL antibody at (A) 1 and (B) 2 μg/ml.)
Immunohistochemistry (IHC)
(Immunohistochemistry of CHADL in mouse skeletal muscle tissue with CHADL antibody at 5 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of CHADL in mouse skeletal muscle tissue with CHADL antibody at 5 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of CHADL in mouse skeletal muscle tissue with CHADL antibody at 20 μg/mL.Red: CHADL Antibody (8423)Blue: DAPI staining)
Immunofluorescence (IF)
(Immunofluorescence of CHADL in mouse skeletal muscle tissue with CHADL antibody at 20 μg/mL.Red: CHADL Antibody (8423)Blue: DAPI staining)
Immunohistochemistry (IHC)
(Immunohistochemistry of CHADL in mouse skeletal muscle tissue with CHADL antibody at 5 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of CHADL in mouse skeletal muscle tissue with CHADL antibody at 5 μg/mL.)
Related Product Information for anti-CHADL antibody
The Chondroadherin-like (CHADL) protein, also known as SLRR4B, is homologous to the Chondroadherin protein and is expressed cartillaginous tissues (1). Like Chondroadherin, CHADL belongs to the small leucine-rich proteoglycan (SLRP) family and class IV subfamily and plays a significant role in the regulation of chondrocyte growth and proliferation (1,2). CHADL is thought to play a negative regualtory role in collagen fibrillogenesis and chondrocyte differentiation (1).
Product Categories/Family for anti-CHADL antibody
References
Tillgren V, Ho JC, Onnerfjord P, et al. The novel small leucine-rich protein chondroadherin-like (CHADL) is expressed in cartilage and modulates chondrocyte differentitation. J. Biol. Chem. 2015; 290:918-25. Neame PJ, Sommarin Y, Boynton RE, et al. The structure of a 38-kDa leucine-rich protein (chondroadherin) isolated from bovine cartilage. J. Biol. Chem. 1994; 269:21547-54.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 84 kDa
Observed: 86 kDa
Observed: 86 kDa
NCBI Official Full Name
chondroadherin-like protein
NCBI Official Synonym Full Names
chondroadherin like
NCBI Official Symbol
CHADL
NCBI Official Synonym Symbols
SLRR4B
NCBI Protein Information
chondroadherin-like protein
UniProt Protein Name
Chondroadherin-like protein
Protein Family
UniProt Gene Name
CHADL
UniProt Synonym Gene Names
SLRR4B
UniProt Entry Name
CHADL_HUMAN
Uniprot Description
CHADL: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class IV subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 22q13.2
Cellular Component: extracellular matrix; proteinaceous extracellular matrix
Molecular Function: collagen binding
Biological Process: negative regulation of chondrocyte differentiation
Research Articles on CHADL
Similar Products
Product Notes
The CHADL chadl (Catalog #AAA154377) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CHADL Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CHADL can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). CHADL antibody can be used for the detection of CHADL by Western blot at 1 - 2 mug/mL. Researchers should empirically determine the suitability of the CHADL chadl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CHADL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
