Western Blot (WB)
(CFHR2 rabbit polyclonal antibody. Western Blot analysis of CFHR2 expression in human liver.)
Rabbit anti-Human CFHR2 Polyclonal Antibody | anti-CFHR2 antibody
CFHR2 (Complement Factor H-related Protein 2, FHR-2, DDESK59, H Factor-like 3, H Factor-like Protein 2, CFHL2, FHR2, HFL3) (Biotin)
Gene Names
CFHR2; FHR2; HFL3; CFHL2
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
CFHR2; Polyclonal Antibody; CFHR2 (Complement Factor H-related Protein 2; FHR-2; DDESK59; H Factor-like 3; H Factor-like Protein 2; CFHL2; FHR2; HFL3) (Biotin); anti-CFHR2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human CFHR2.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-CFHR2 antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length human CFHR2, aa1-270 (NP_005657.1).
Immunogen Sequence
MWLLVSVILISRISSVGGEAMFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFVSPSKSFWTRITCAEEGWSPTPKCLRLCFFPFVENGHSESSGQTHLEGDTVQIICNTGYRLQNNENNISCVERGWSTPPKCRSTISAEKCGPPPPIDNGDITSFLLSVYAPGSSVEYQCQNLYQLEGNNQITCRNGQWSEPPKCLDPCVISQEIMEKYNIKLKWTNQQKLYSRTGDIVEFVCKSGYHPTKSHSFRAMCQNGKLVYPSCEEK
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(CFHR2 rabbit polyclonal antibody. Western Blot analysis of CFHR2 expression in human liver.)
Western Blot (WB)
(CFHR2 rabbit polyclonal antibody. Western Blot analysis of CFHR2 expression in human liver.)
Western Blot (WB)
(Western Blot analysis of CFHR2 expression in transfected 293T cell line by CFHR2 polyclonal antibody. Lane 1: CFHR2 transfected lysate (30.7kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of CFHR2 expression in transfected 293T cell line by CFHR2 polyclonal antibody. Lane 1: CFHR2 transfected lysate (30.7kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-CFHR2 antibody
Might be involved in complement regulation. Can associate with lipoproteins and may play a role in lipid metabolism.
Product Categories/Family for anti-CFHR2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27,897 Da
NCBI Official Full Name
complement factor H-related protein 2 isoform 1
NCBI Official Synonym Full Names
complement factor H related 2
NCBI Official Symbol
CFHR2
NCBI Official Synonym Symbols
FHR2; HFL3; CFHL2
NCBI Protein Information
complement factor H-related protein 2
UniProt Protein Name
Complement factor H-related protein 2
Protein Family
UniProt Gene Name
CFHR2
UniProt Synonym Gene Names
CFHL2; FHR2; HFL3; FHR-2
NCBI Description
This gene belongs to a family of complement factor H-related genes (CFHR), which are clustered together with complement factor H gene on chromosome 1, and are involved in regulation of complement. Mutations in CFHR genes have been associated with dense deposit disease and atypical haemolytic-uraemic syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015]
Uniprot Description
Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism.
Research Articles on CFHR2
1. Studies indicate an association between CFHR2-rs2986127 and acute anterior uveitis (AAU) diagnosis.
Similar Products
Product Notes
The CFHR2 cfhr2 (Catalog #AAA6373787) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CFHR2 (Complement Factor H-related Protein 2, FHR-2, DDESK59, H Factor-like 3, H Factor-like Protein 2, CFHL2, FHR2, HFL3) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CFHR2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CFHR2 cfhr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CFHR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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