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Western Blot (WB) (Western Blot analysis of MCF-7 cells using Cerberus Polyclonal Antibody.)

Rabbit Cerberus Polyclonal Antibody | anti-Cerberus antibody

Cerberus Polyclonal Antibody

Gene Names
CER1; DAND4
Applications
Western Blot, ELISA
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
Cerberus; Polyclonal Antibody; Cerberus Polyclonal Antibody; CER1; DAND4; Cerberus-related protein; DAN domain family member 4; anti-Cerberus antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Specificity
Cerberus Polyclonal Antibody detects endogenous levels of Cerberus protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
267
Applicable Applications for anti-Cerberus antibody
Western Blot (WB), ELISA (EIA)
Application Notes
Western Blot: 1:500 - 1:2000
ELISA: 1:20000
Not yet tested in other applications.
Immunogen Type
peptide
Immunogen Description
Synthesized peptide derived from the Internal region of human Cerberus.
Target Name
Cerberus
Preparation and Storage
Store at -20 degree C/1 year

Western Blot (WB)

(Western Blot analysis of MCF-7 cells using Cerberus Polyclonal Antibody.)

Western Blot (WB) (Western Blot analysis of MCF-7 cells using Cerberus Polyclonal Antibody.)
Product Categories/Family for anti-Cerberus antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
30,084 Da
NCBI Official Full Name
cerberus
NCBI Official Synonym Full Names
cerberus 1, DAN family BMP antagonist
NCBI Official Symbol
CER1
NCBI Official Synonym Symbols
DAND4
NCBI Protein Information
cerberus
UniProt Protein Name
Cerberus
Protein Family
UniProt Gene Name
CER1
UniProt Synonym Gene Names
DAND4
UniProt Entry Name
CER1_HUMAN

NCBI Description

This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008]

Uniprot Description

CER1: Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak. Belongs to the DAN family.

Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 9p23-p22

Cellular Component: extracellular space; extracellular region

Molecular Function: morphogen activity; protein homodimerization activity; cytokine activity

Biological Process: nervous system development; negative regulation of Wnt receptor signaling pathway; gastrulation; determination of dorsal identity; bone mineralization; negative regulation of BMP signaling pathway; anterior/posterior pattern formation; BMP signaling pathway; negative regulation of activin receptor signaling pathway; negative regulation of cell proliferation; ureteric bud development; cell migration involved in gastrulation; anterior/posterior axis specification

Research Articles on Cerberus

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Product Notes

The Cerberus cer1 (Catalog #AAA9410959) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Cerberus can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). Western Blot: 1:500 - 1:2000 ELISA: 1:20000 Not yet tested in other applications. Researchers should empirically determine the suitability of the Cerberus cer1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cerberus, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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