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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded rat brain slide using MBS7612074(CEP350 Antibody) at dilution of 1:50)

Rabbit anti-Human, Rat CEP350 Polyclonal Antibody | anti-CEP350 antibody

anti-CEP350 antibody

Gene Names
CEP350; GM133; CAP350
Reactivity
Human, Rat
Applications
ELISA, Immunohistochemistry, Immunofluorescence
Purity
>=95% as determined by SDS-PAGE. Immunogen affinity purified
Synonyms
CEP350; Polyclonal Antibody; anti-CEP350 antibody; CAP350; centrosomal protein 350kDa; GM133; KIAA0480
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE. Immunogen affinity purified
Form/Format
Liquid. PBS with 0.02% sodium azide and 50% glycerol pH7.3
Applicable Applications for anti-CEP350 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
IHC: 1:20-1:200
IF: 1:10-1:100
Immunogen
centrosomal protein 350kDa
Preparation and Storage
Store at -20 degree C for 12 months. Avoid repeated freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded rat brain slide using MBS7612074(CEP350 Antibody) at dilution of 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded rat brain slide using MBS7612074(CEP350 Antibody) at dilution of 1:50)
Product Categories/Family for anti-CEP350 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
350,930 Da
NCBI Official Full Name
centrosome-associated protein 350
NCBI Official Synonym Full Names
centrosomal protein 350kDa
NCBI Official Symbol
CEP350
NCBI Official Synonym Symbols
GM133; CAP350
NCBI Protein Information
centrosome-associated protein 350
UniProt Protein Name
Centrosome-associated protein 350
UniProt Gene Name
CEP350
UniProt Synonym Gene Names
CAP350; KIAA0480; Cep350
UniProt Entry Name
CE350_HUMAN

NCBI Description

The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

CEP350: Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ. Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network. Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity.

Protein type: Nuclear receptor co-regulator; Cell cycle regulation

Chromosomal Location of Human Ortholog: 1q25.2

Cellular Component: nucleoplasm; centrosome; membrane; cytoplasm; spindle

Molecular Function: protein binding; microtubule binding

Research Articles on CEP350

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Product Notes

The CEP350 cep350 (Catalog #AAA7612074) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The anti-CEP350 antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CEP350 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF). IHC: 1:20-1:200 IF: 1:10-1:100. Researchers should empirically determine the suitability of the CEP350 cep350 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CEP350, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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