Immunofluorescence (IF)
(Sample Type : DNA/ACA)
Rabbit anti-Human CENPI Polyclonal Antibody | anti-CENPI antibody
CENPI antibody - N-terminal region
Immunofluorescence (IF)
(Sample Type : DNA/ACA)
Immunofluorescence (IF)
(Sample Type : DNA/ACA)
Western Blot (WB)
(WB Suggested Anti-CENPI Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysateCENPI is strongly supported by BioGPS gene expression data to be expressed in Human MCF7 cells)
Western Blot (WB)
(WB Suggested Anti-CENPI Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysateCENPI is strongly supported by BioGPS gene expression data to be expressed in Human MCF7 cells)
Target Description: CENPI is involved in the response of gonadal tissues to follicle-stimulating hormone. The gene encoding CENPI is also a potential candidate for human X-linked disorders of gonadal development and gametogenesis. The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. This gene is also a potential candidate for human X-linked disorders of gonadal development and gametogenesis.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a centromere protein that is a component of the CENPA-NAC (nucleosome-associated) complex. This complex is critical for accurate chromosome alignment and segregation and it ensures proper mitotic progression. This protein regulates the recruitment of kinetochore-associated proteins that are required to generate the spindle checkpoint signal. The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. Mutations in this gene may be involved in human X-linked disorders of gonadal development and gametogenesis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 13. [provided by RefSeq, Jan 2016]
Uniprot Description
CENPI: involved in the response of gonadal tissues to follicle-stimulating hormone. Highly expressed in testis, ovary and spleen.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: Xq22.1
Cellular Component: kinetochore; nucleoplasm; cytoplasm; nucleus; cytosol
Molecular Function: protein binding
Biological Process: nucleosome assembly; DNA replication-independent nucleosome assembly at centromere; mitotic cell cycle; sex differentiation
Research Articles on CENPI
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Product Notes
The CENPI cenpi (Catalog #AAA3211873) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CENPI antibody - N-terminal region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CENPI can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Western Blot (WB). Researchers should empirically determine the suitability of the CENPI cenpi for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: SPQKRVKNVQ AQNRTSQGSS SFQTTLSAWK VKQDPSNSKN ISKHGQNNPV. It is sometimes possible for the material contained within the vial of "CENPI, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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