Rabbit anti-Mouse CEBPE Polyclonal Antibody | anti-CEBPE antibody

CEBPE Rabbit pAb

Cat. Num. AAA4754259

• Gene Names: CEBPE; CRP1; C/EBP-epsilon
• Reactivity: Mouse
• Applications: ELISA, Western Blot
• Purity: Affinity purified
• Synonyms: CEBPE; Polyclonal Antibody; CEBPE Rabbit pAb; CRP1; C/EBP-epsilon; anti-CEBPE antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Purity/Purification: Affinity purified
• Form/Format: -20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

• Applicable Applications for anti-CEBPE antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: WB: 1:200-1:1000
• Immunogen: Fusion protein of human CEBPE
• Conjugation: Unconjugated
• Molecular Function: The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined.
• Modification: Unmodified
• Cell Position: Nucleus
• Preparation and Storage: Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Gel: 10%SDS-PAGE, Lysate: 40 ug, Lane: Mouse liver tissue, Primary antibody: 120412(CEBPE Antibody) at dilution 1/650, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds)

Product Categories/Family for anti-CEBPE antibody

Primary antibody

NCBI and Uniprot Product Information

• NCBI GI #: 23272762
• NCBI GeneID: 1053
• UniProt Accession #: Q15744; Q15745; Q8IYI2; Q99803
• Molecular Weight: 30,603 Da
• NCBI Official Full Name: Homo sapiens CCAAT/enhancer binding protein (C/EBP), epsilon, mRNA
• NCBI Official Synonym Full Names: CCAAT/enhancer binding protein epsilon
• NCBI Official Symbol: CEBPE
• NCBI Official Synonym Symbols: CRP1; C/EBP-epsilon
• NCBI Protein Information: CCAAT/enhancer-binding protein epsilon
• UniProt Protein Name: CCAAT/enhancer-binding protein epsilon
• Protein Family: CCAAT/enhancer-binding protein
• UniProt Gene Name: CEBPE
• UniProt Synonym Gene Names: C/EBP epsilon
• UniProt Entry Name: CEBPE_HUMAN

NCBI Description

The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

C/EBP-epsilon: C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Belongs to the bZIP family. C/EBP subfamily.

Protein type: Transcription factor; Motility/polarity/chemotaxis; DNA-binding

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: nucleoplasm

Molecular Function: protein homodimerization activity; protein heterodimerization activity

Biological Process: macrophage differentiation; transcription, DNA-dependent; cytokine biosynthetic process; defense response to bacterium; positive regulation of transcription from RNA polymerase II promoter; defense response; phagocytosis

Disease: Specific Granule Deficiency