Western Blot (WB)
((1ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat CDX2 Polyclonal Antibody | anti-CDX2 antibody
Goat anti-CDX2 Antibody
Western Blot: Approx 38kDa band observed in Human Kidney and Liver lysates (calculated MW of 33.5kDa according to NP_001256.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Qualtrough et al Gut.2002 Aug;51(2): 184-90; PMID: 12117877). Recommended concentration: 1-3ug/ml.
Western Blot (WB)
((1ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((1ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012]
Uniprot Description
CDX2: Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Belongs to the Caudal homeobox family.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 13q12.3
Cellular Component: condensed nuclear chromosome; nucleoplasm; nucleus; transcriptional repressor complex
Molecular Function: transcription corepressor activity; transcription factor activity
Biological Process: anterior/posterior axis specification; blood vessel development; cell differentiation; endosome to lysosome transport; establishment and/or maintenance of epithelial cell polarity; negative regulation of transcription from RNA polymerase II promoter; organ morphogenesis; positive regulation of cell differentiation; positive regulation of cell proliferation; positive regulation of transcription, DNA-dependent; regulation of somitogenesis; somatic stem cell maintenance; transcription from RNA polymerase II promoter; trophectodermal cell differentiation
Research Articles on CDX2
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Product Notes
The CDX2 cdx2 (Catalog #AAA420404) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-CDX2 Antibody reacts with Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's CDX2 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 4000. Western Blot: Approx 38kDa band observed in Human Kidney and Liver lysates (calculated MW of 33.5kDa according to NP_001256.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Qualtrough et al Gut.2002 Aug;51(2): 184-90; PMID: 12117877). Recommended concentration: 1-3ug/ml. Researchers should empirically determine the suitability of the CDX2 cdx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: EQLSPGGQRR NLCE. It is sometimes possible for the material contained within the vial of "CDX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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