Western Blot (WB)
(Western blot analysis CDKL5 using K562 whole cell lysates)
Rabbit anti-Human, Mouse CDKL5 Polyclonal Antibody | anti-CDKL5 antibody
CDKL5 Antibody
Western Blot (WB)
(Western blot analysis CDKL5 using K562 whole cell lysates)
Western Blot (WB)
(Western blot analysis CDKL5 using K562 whole cell lysates)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of Ser/Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
Uniprot Description
CDKL5: a protein kinase of the CDKL family. Mutations have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized.
Protein type: CDKL family; CMGC group; Cell cycle regulation; EC 2.7.11.22; Kinase, protein; Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: Xp22
Cellular Component: cytoplasm; dendrite cytoplasm; nucleoplasm; nucleus
Molecular Function: ATP binding; kinase activity; protein kinase activity; protein serine/threonine kinase activity; Rac GTPase binding
Biological Process: neuron migration; positive regulation of axon extension; positive regulation of dendrite morphogenesis; positive regulation of GTPase activity; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of dendrite development
Disease: Epileptic Encephalopathy, Early Infantile, 2
Research Articles on CDKL5
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Product Notes
The CDKL5 cdkl5 (Catalog #AAA9418869) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDKL5 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CDKL5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000-3000. Researchers should empirically determine the suitability of the CDKL5 cdkl5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDKL5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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