Testing Data
(Gel: 6%SDS-PAGE Lysates (from left to right): Human normal liver tissue Amount of lysate: 40ug per lane Primary antibody: 1/655 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 second)
Rabbit anti-Human CDK5RAP3 Polyclonal Antibody | anti-CDK5RAP3 antibody
CDK5RAP3 Antibody
Immunohistochemistry: 1:50-1:200
Testing Data
(Gel: 6%SDS-PAGE Lysates (from left to right): Human normal liver tissue Amount of lysate: 40ug per lane Primary antibody: 1/655 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 second)
Testing Data
(Gel: 6%SDS-PAGE Lysates (from left to right): Human normal liver tissue Amount of lysate: 40ug per lane Primary antibody: 1/655 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 second)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/60.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/60.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013]
Uniprot Description
CDK5RAP3: Potential regulator of CDK5 activity. May be involved in cell proliferation. Regulates CDK5 activity via its interaction with CDK5R1. Belongs to the CDK5RAP3 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 17q21.32
Cellular Component: protein complex; membrane; cytoplasm; nucleolus; endomembrane system; nucleus
Molecular Function: cyclin binding; protein binding; protein kinase binding
Biological Process: cell proliferation; positive regulation of protein ubiquitination; regulation of neuron differentiation; inhibition of NF-kappaB transcription factor; regulation of mitotic cell cycle; positive regulation of transcription from RNA polymerase II promoter; brain development; regulation of cyclin-dependent protein kinase activity
Research Articles on CDK5RAP3
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Product Notes
The CDK5RAP3 cdk5rap3 (Catalog #AAA9407468) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDK5RAP3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CDK5RAP3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:200-1:1000 Immunohistochemistry: 1:50-1:200. Researchers should empirically determine the suitability of the CDK5RAP3 cdk5rap3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDK5RAP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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