Rabbit anti-Mouse Cdk20 Polyclonal Antibody | anti-Cdk20 antibody

Cdk20, ID (Cdk20, Ccrk, Cdch, Cyclin-dependent kinase 20, CDK-activating kinase p42, CDK-related protein kinase PNQLARE, Cell cycle-related kinase, Cell division protein kinase 20, Cyclin-dependent protein kinase H, Cyclin-kinase-activating kinase p42) (F

Cat. Num. AAA6284350

• Gene Names: Cdk20; p42; CDCH; Ccrk; PNQLARE; AU019450; AW558027; 4932702G04Rik
• Reactivity: Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: Cdk20; Polyclonal Antibody; ID (Cdk20; Ccrk; Cdch; Cyclin-dependent kinase 20; CDK-activating kinase p42; CDK-related protein kinase PNQLARE; Cell cycle-related kinase; Cell division protein kinase 20; Cyclin-dependent protein kinase H; Cyclin-kinase-activating kinase p42) (F; Cyclin-kinase-activating kinase p42; anti-Cdk20 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-Cdk20 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: Mouse Cdk20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-212 amino acids from the Central region of Mouse Cdk20.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Mouse Cdk20 Antibody (Center) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the Cdk20 antibody detected the Cdk20 protein (arrow).)

Related Product Information for anti-Cdk20 antibody

Cdk20 is involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160' (By similarity). Required for high-level Shh responses in the developing neural tube. Together with BROMI, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling.

Product Categories/Family for anti-Cdk20 antibody

Antibodies; Protein Kinases

References

Qiu, H., et al. J. Biol. Chem. 283(32):22157-22165(2008). Wohlbold, L., et al. Cell Cycle 5(5):546-554(2006).

NCBI and Uniprot Product Information

• NCBI GI #: 16716469
• NCBI GeneID: 105278
• NCBI Accession #: NP_444410.1
• NCBI GenBank Nucleotide #: NM_053180.2
• UniProt Accession #: Q9JHU3; Q5EDC2
• Molecular Weight: 26,974 Da
• NCBI Official Full Name: cyclin-dependent kinase 20
• NCBI Official Synonym Full Names: cyclin-dependent kinase 20
• NCBI Official Symbol: Cdk20
• NCBI Official Synonym Symbols: p42; CDCH; Ccrk; PNQLARE; AU019450; AW558027; 4932702G04Rik
• NCBI Protein Information: cyclin-dependent kinase 20
• UniProt Protein Name: Cyclin-dependent kinase 20
• Protein Family: Cyclin-dependent kinase
• UniProt Gene Name: Cdk20
• UniProt Synonym Gene Names: Ccrk; Cdch; CAK-kinase p42

Uniprot Description

Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160' (). Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling.