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Western Blot (WB) (Western blotAll lanes: CDK16 antibody at 5ug/mlLane 1:mouse brain tissueLane 2:mouse small intestine tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 56,64,57 kDaObserved band size: 56 kDa)

Rabbit anti-Human, Mouse CDK16 Polyclonal Antibody | anti-CDK16 antibody

CDK16 Antibody

Gene Names
CDK16; PCTK1; PCTAIRE; PCTAIRE1; PCTGAIRE
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
CDK16; Polyclonal Antibody; CDK16 Antibody; Cell division protein kinase 16; PCTAIRE-motif protein kinase 1; Serine/threonine-protein kinase PCTAIRE-1; PCTAIRE1; PCTK1; anti-CDK16 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
570
Applicable Applications for anti-CDK16 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: WB:1:200-1000
IHC:1:20-1:200
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Cyclin-dependent kinase 16 protein (277-496aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-174 / sc-22775
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: CDK16 antibody at 5ug/mlLane 1:mouse brain tissueLane 2:mouse small intestine tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 56,64,57 kDaObserved band size: 56 kDa)

Western Blot (WB) (Western blotAll lanes: CDK16 antibody at 5ug/mlLane 1:mouse brain tissueLane 2:mouse small intestine tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 56,64,57 kDaObserved band size: 56 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human placenta tissueusing MBS1499828 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human placenta tissueusing MBS1499828 at dilution 1:100)
Related Product Information for anti-CDK16 antibody
Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development (By similarity). Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser-336' (in vitro).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
56,375 Da
NCBI Official Full Name
cyclin-dependent kinase 16 isoform 3
NCBI Official Synonym Full Names
cyclin-dependent kinase 16
NCBI Official Symbol
CDK16
NCBI Official Synonym Symbols
PCTK1; PCTAIRE; PCTAIRE1; PCTGAIRE
NCBI Protein Information
cyclin-dependent kinase 16
UniProt Protein Name
Cyclin-dependent kinase 16
Protein Family
UniProt Gene Name
CDK16
UniProt Synonym Gene Names
PCTAIRE1; PCTK1
UniProt Entry Name
CDK16_HUMAN

NCBI Description

The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2009]

Uniprot Description

CDK16: May play a role in signal transduction cascades in terminally differentiated cells. Found in a complex containing CABLES1, CDK17 and TDRD7. Interacts with YWHAH, YWHAQ and YWHAZ. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

Protein type: Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Cell cycle regulation; EC 2.7.11.22; Protein kinase, CMGC; Motility/polarity/chemotaxis; CMGC group; CDK family; CDK/TAIRE subfamily; TAIRE subfamily

Chromosomal Location of Human Ortholog: Xp11

Cellular Component: cell junction; cytoplasm; extrinsic to internal side of plasma membrane; microtubule cytoskeleton; neuron projection; plasma membrane; synaptic vesicle

Molecular Function: ATP binding; cyclin-dependent protein kinase activity; protein binding; protein serine/threonine kinase activity

Biological Process: exocytosis; growth hormone secretion; neurite development; protein amino acid phosphorylation; regulation of cell cycle; spermatogenesis

Research Articles on CDK16

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Product Notes

The CDK16 cdk16 (Catalog #AAA1499828) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDK16 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CDK16 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Recommended dilution: WB:1:200-1000 IHC:1:20-1:200. Researchers should empirically determine the suitability of the CDK16 cdk16 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDK16, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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