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Immunohistochemistry (IHC) (Anti-CDHR5 / MUPCDH antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit CDHR5 / MUCDHL Polyclonal Antibody | anti-CDHR5 antibody

Rabbit Polyclonal to Human CDHR5 / MUCDHL

Gene Names
CDHR5; MUCDHL; MUPCDH; MU-PCDH
Reactivity
Gorilla, Human
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
CDHR5 / MUCDHL; Polyclonal Antibody; Rabbit Polyclonal to Human CDHR5 / MUCDHL; Anti-CDHR5 / MUCDHL Antibody (Cytoplasmic Domain) IHC-plus; CDHR5; Mu-protocadherin; Mucin and cadherin-like; MUPCDH; Mucin-like protocadherin; MU-PCDH; MUCDHL; MUCDHL-ALT; MUCDHL-FL; Human CDHR5; anti-CDHR5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Gorilla, Human
Clonality
Polyclonal
Specificity
Human CDHR5 / MUPCDH. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
845
Applicable Applications for anti-CDHR5 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (5 - 7.5 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from cytoplasmic domain of human CDHR5 / MUPCDH. Percent identity with other species by BLAST analysis: Human, Gorilla (100%).
Immunogen Type
Synthetic peptide
Immunogen
CDHR5 / MUCDHL antibody was raised against synthetic 17 amino acid peptide from cytoplasmic domain of human CDHR5 / MUPCDH. Percent identity with other species by BLAST analysis: Human, Gorilla (100%).
Antigen Modification
Cytoplasmic Domain
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-CDHR5 / MUPCDH antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-CDHR5 / MUPCDH antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-CDHR5 / MUPCDH antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-CDHR5 / MUPCDH antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-CDHR5 antibody
Mucin-like protocadherin is a developmentally regulated cell adhesion molecule that contains an extracellular region with four cadherin-like ectodomains and a triply repeating mucin domain in its' longer isoform. This later domain is known to negatively regulate cadherin function in carcinoma cells. During development, MUCDHL functions in the generation of the three-dimensional structure of the kidney. In adult kidney it is localized to the brush border of the proximal convoluted tubule.
Product Categories/Family for anti-CDHR5 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
87,631 Da
NCBI Official Full Name
cadherin-related family member 5 isoform 1
NCBI Official Synonym Full Names
cadherin-related family member 5
NCBI Official Symbol
CDHR5
NCBI Official Synonym Symbols
MUCDHL; MUPCDH; MU-PCDH
NCBI Protein Information
cadherin-related family member 5; mu-protocadherin; mucin and cadherin-like protein
UniProt Protein Name
Cadherin-related family member 5
Protein Family
UniProt Gene Name
CDHR5
UniProt Synonym Gene Names
MUCDHL; MUPCDH
UniProt Entry Name
CDHR5_HUMAN

NCBI Description

This gene is a novel mucin-like gene that is a member of the cadherin superfamily. While encoding nonpolymorphic tandem repeats rich in proline, serine and threonine similar to mucin proteins, the gene also contains sequence encoding calcium-binding motifs found in all cadherins. The role of the hybrid extracellular region and the specific function of this protein have not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jan 2010]

Uniprot Description

MUCDHL: Acts as a calcium-dependent cell adhesion protein. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: integral to membrane; plasma membrane

Molecular Function: protein binding; beta-catenin binding; calcium ion binding

Biological Process: homophilic cell adhesion; cell adhesion

Research Articles on CDHR5

Similar Products

Product Notes

The CDHR5 cdhr5 (Catalog #AAA247389) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human CDHR5 / MUCDHL reacts with Gorilla, Human and may cross-react with other species as described in the data sheet. AAA Biotech's CDHR5 / MUCDHL can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (5 - 7.5 ug/ml). Researchers should empirically determine the suitability of the CDHR5 cdhr5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDHR5 / MUCDHL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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