Western Blot (WB)
(CDH22 Antibody (Center) western blot analysis in HepG2,293,K562 cell line lysates (35ug/lane).This demonstrates the CDH22 antibody detected the CDH22 protein (arrow).)
Rabbit anti-Human CDH22 Polyclonal Antibody | anti-CDH22 antibody
CDH22 Antibody (Center)
Western Blot (WB)
(CDH22 Antibody (Center) western blot analysis in HepG2,293,K562 cell line lysates (35ug/lane).This demonstrates the CDH22 antibody detected the CDH22 protein (arrow).)
Western Blot (WB)
(CDH22 Antibody (Center) western blot analysis in HepG2,293,K562 cell line lysates (35ug/lane).This demonstrates the CDH22 antibody detected the CDH22 protein (arrow).)
Immunohistochemistry (IHC)
(CDH22 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CDH22 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(CDH22 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CDH22 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
gene product is composed of five cadherin repeat domains and a
cytoplasmic tail similar to the highly conserved cytoplasmic region
of classical cadherins. Expressed predominantly in the brain, this
putative calcium-dependent cell adhesion protein may play an
important role in morphogenesis and tissue formation in neural and
non-neural cells during development and maintenance of the brain
and neuroendocrine organs.
Liu, Y., et al. Cancer Biol. Ther. 8(14):1352-1359(2009)
Zhou, J., et al. Tumour Biol. 30(3):130-140(2009)
Bento, J.L., et al. Genomics 92(4):226-234(2008)
Wu, J., et al. J. Endocrinol. 176(3):381-391(2003)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the cadherin superfamily. The gene product is composed of five cadherin repeat domains and a cytoplasmic tail similar to the highly conserved cytoplasmic region of classical cadherins. Expressed predominantly in the brain, this putative calcium-dependent cell adhesion protein may play an important role in morphogenesis and tissue formation in neural and non-neural cells during development and maintenance of the brain and neuroendocrine organs. [provided by RefSeq, Jul 2008]
Uniprot Description
CDH22: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. PB-cadherins may have a role in the morphological organization of pituitary gland and brain tissues.
Protein type: Membrane protein, integral; Cell adhesion
Chromosomal Location of Human Ortholog: 20q13.1
Cellular Component: plasma membrane; integral to membrane
Molecular Function: calcium ion binding
Biological Process: calcium-dependent cell-cell adhesion; brain development; homophilic cell adhesion
Research Articles on CDH22
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Product Notes
The CDH22 cdh22 (Catalog #AAA9206691) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 411-440. The CDH22 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CDH22 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the CDH22 cdh22 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDH22, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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