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Western Blot (WB) (Western blot analysis of extracts from Jurkat cells and HUVEC cells, using CDH17 antibody.)

Rabbit anti-Human CDH17 Polyclonal Antibody | anti-CDH17 antibody

CDH17 Antibody

Gene Names
CDH17; HPT1; CDH16; HPT-1
Reactivity
Human
Applications
Western Blot, Immunofluorescence
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
CDH17; Polyclonal Antibody; CDH17 Antibody; CAD17; CADH; Intestinal peptide-associated transporter HPT-1; LI-cad; LI-cadherin; anti-CDH17 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total CDH17 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
832
Applicable Applications for anti-CDH17 antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes
Western blotting: 1:500~1:3000
Immunofluorescence: 1:100~1:500
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from internal of human CDH17.
Target Name
CDH17
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from Jurkat cells and HUVEC cells, using CDH17 antibody.)

Western Blot (WB) (Western blot analysis of extracts from Jurkat cells and HUVEC cells, using CDH17 antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of HeLa cells, using CDH17 antibody.)

Immunofluorescence (IF) (Immunofluorescence analysis of HeLa cells, using CDH17 antibody.)
Related Product Information for anti-CDH17 antibody
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.Dantzig A.H., Science 264:430-433(1994).Boettinger A., Submitted (DEC-1994) to the EMBL/GenBank/DDBJ databases.Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Product Categories/Family for anti-CDH17 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
92,219 Da
NCBI Official Full Name
cadherin-17
NCBI Official Synonym Full Names
cadherin 17, LI cadherin (liver-intestine)
NCBI Official Symbol
CDH17
NCBI Official Synonym Symbols
HPT1; CDH16; HPT-1
NCBI Protein Information
cadherin-17
UniProt Protein Name
Cadherin-17
Protein Family
UniProt Gene Name
CDH17
UniProt Synonym Gene Names
LI-cadherin
UniProt Entry Name
CAD17_HUMAN

NCBI Description

This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]

Uniprot Description

CDH17: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 8q22.1

Cellular Component: basolateral plasma membrane; plasma membrane; integral to membrane

Molecular Function: transporter activity; calcium ion binding; proton-dependent oligopeptide secondary active transmembrane transporter activity

Biological Process: intercellular junction assembly and maintenance; transport; calcium-dependent cell-cell adhesion; cell adhesion; homophilic cell adhesion; oligopeptide transport

Research Articles on CDH17

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Product Notes

The CDH17 cdh17 (Catalog #AAA9410007) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDH17 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CDH17 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). Western blotting: 1:500~1:3000 Immunofluorescence: 1:100~1:500. Researchers should empirically determine the suitability of the CDH17 cdh17 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDH17, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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