Immunohistochemistry (IHC)
(Immunochemical staining of human CDC37L1 in human liver with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human CDC37L1 Polyclonal Antibody | anti-CDC37L1 antibody
Anti-CDC37L1 Antibody, Rabbit Polyclonal
Gene Names
CDC37L1; HARC; CDC37B
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
CDC37L1; Polyclonal Antibody; Anti-CDC37L1 Antibody; Rabbit Polyclonal; CDC37L1 Antibody; Rabbit PAb; Antigen Affinity Purified; Anti-HARC Antibody; Anti-RP11-6J24.5 Antibody; anti-CDC37L1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human CDC37L1
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-CDC37L1 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:200-1:1000
Immunogen
A synthetic peptide corresponding to the N-terminus of the Human CDC37L1
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human CDC37L1, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human CDC37L1 in human liver with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human CDC37L1 in human liver with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-CDC37L1 antibody
The Hsp90 cochaperone CDC37 recruits Hsp90 to protein kinases as well as inhibiting its ATPase activity to promote the binding of Hsp90 to protein kinases. CDC37L1 (Cell Division Cycle 37 Like 1, also known as HARC and CDC37B) is a cytoplasmic phosphoprotein that exists in complex with HSP90 as well as several other proteins involved in HSP90-mediated protein folding. HARC is a structurally related Hsp90 cochaperone with a three-domain structure in which the middle domain binds Hsp90. In contrast to CDC37 though, HARC also binds to Hsp70 and Hop (Hsp70/Hsp90 organizing protein). CDC37L1 is associated with some diseases, including Ulceroglandular Tularemia and Delusional Disorder.
References
Cartledge K, et al. (2007) Importance of the c-terminal domain of harc for binding to hsp70 and hop as well as its response to heat shock. Biochemistry 46 (51): 15144-15152.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38,835 Da
NCBI Official Full Name
hsp90 co-chaperone Cdc37-like 1
NCBI Official Synonym Full Names
cell division cycle 37-like 1
NCBI Official Symbol
CDC37L1
NCBI Official Synonym Symbols
HARC; CDC37B
NCBI Protein Information
hsp90 co-chaperone Cdc37-like 1; CDC37 cell division cycle 37 homolog-like 1; Hsp90-associating relative of Cdc37
UniProt Protein Name
Hsp90 co-chaperone Cdc37-like 1
Protein Family
UniProt Gene Name
CDC37L1
UniProt Synonym Gene Names
CDC37B; HARC
UniProt Entry Name
CD37L_HUMAN
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Product Notes
The CDC37L1 cdc37l1 (Catalog #AAA8101371) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CDC37L1 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CDC37L1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:200-1:1000. Researchers should empirically determine the suitability of the CDC37L1 cdc37l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDC37L1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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