Rabbit CDC37 Polyclonal Antibody | anti-CDC37 antibody

CDC37 Antibody

Cat. Num. AAA7121866

• Gene Names: CDC37; P50CDC37
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: CDC37; Polyclonal Antibody; CDC37 Antibody; CDC37A; Hsp90 co-chaperone Cdc37; Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37; anti-CDC37 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Liquid; In Phosphate Buffered Saline, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.

• Applicable Applications for anti-CDC37 antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
• Application Notes: WB: 1:500-1:2000; IHC: 1:100-1:300; IF: 1:200-1:1000; ELISA: 1:20000
• Immunogen: Synthesized peptide derived from the Internal region of human Cdc37.
• Immunogen Species: Human
• Conjugate: Non-conjugated
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western Blot analysis of 3T3 cells using Cdc37 Polyclonal Antibody)

Western Blot (WB)

(Western Blot analysis of various cells using Cdc37 Polyclonal Antibody)

Product Categories/Family for anti-CDC37 antibody

Cell Biology

NCBI and Uniprot Product Information

• NCBI GI #: 5901922
• NCBI GeneID: 11140
• NCBI Accession #: NP_008996.1
• NCBI GenBank Nucleotide #: NM_007065.3
• UniProt Accession #: Q16543; Q53YA2
• Molecular Weight: 44,468 Da
• NCBI Official Full Name: hsp90 co-chaperone Cdc37
• NCBI Official Synonym Full Names: cell division cycle 37
• NCBI Official Symbol: CDC37
• NCBI Official Synonym Symbols: P50CDC37
• NCBI Protein Information: hsp90 co-chaperone Cdc37; cell division cycle 37 homolog; CDC37 cell division cycle 37 homolog; hsp90 chaperone protein kinase-targeting subunit; CDC37 (cell division cycle 37, S. cerevisiae, homolog)
• UniProt Protein Name: Hsp90 co-chaperone Cdc37
• Protein Family: Hsp90 co-chaperone
• UniProt Gene Name: CDC37
• UniProt Synonym Gene Names: CDC37A
• UniProt Entry Name: CDC37_HUMAN

NCBI Description

The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008]

Uniprot Description

CDC37: a molecular chaperone that functions in cell signal transduction. Forms complexes with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. Also interacts with androgen receptor. It is thought to play a critical role in directing Hsp90 to its target kinases.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: protein complex; cytoplasm; cytosol

Molecular Function: protein kinase B binding; protein binding; heat shock protein binding; chaperone binding; unfolded protein binding; Hsp90 protein binding; mitogen-activated protein kinase kinase kinase binding; kinase binding

Biological Process: protein stabilization; protein folding; regulation of cyclin-dependent protein kinase activity; protein targeting