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Western Blot (WB) (Western blot analysis CD88 (Phospho-Ser327) using COLO205 whole cell lysates)

Rabbit anti-Human CD88 Polyclonal Antibody | anti-CD88 antibody

CD88 (Phospho-Ser327) Antibody

Gene Names
C5AR1; C5A; C5AR; C5R1; CD88
Reactivity
Human
Applications
Western Blot
Purity
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Synonyms
CD88; Polyclonal Antibody; CD88 (Phospho-Ser327) Antibody; C5AR1; C5A; C5a-R; C5a ligand; C5a receptor; C5a anaphylatoxin receptor; C5AR; C5R1; CD88 antigen; anti-CD88 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
CD88 (Phospho-Ser327) Antibody detects endogenous levels of CD88 only when phosphorylated at Ser327
Purity/Purification
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
350
Applicable Applications for anti-CD88 antibody
Western Blot (WB)
Application Notes
Western Blot: 1:1000
Immunogen
A synthesized peptide derived from human CD88 (Phospho-Ser327)
Immunogen Type
Peptide
Modification
Phospho-Ser327
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis CD88 (Phospho-Ser327) using COLO205 whole cell lysates)

Western Blot (WB) (Western blot analysis CD88 (Phospho-Ser327) using COLO205 whole cell lysates)
Product Categories/Family for anti-CD88 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
728
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39,336 Da
NCBI Official Full Name
C5a anaphylatoxin chemotactic receptor 1
NCBI Official Synonym Full Names
complement C5a receptor 1
NCBI Official Symbol
C5AR1
NCBI Official Synonym Symbols
C5A; C5AR; C5R1; CD88
NCBI Protein Information
C5a anaphylatoxin chemotactic receptor 1
UniProt Protein Name
C5a anaphylatoxin chemotactic receptor 1
UniProt Gene Name
C5AR1
UniProt Synonym Gene Names
C5AR; C5R1; C5a-R; C5aR
UniProt Entry Name
C5AR1_HUMAN

Uniprot Description

C5aR: a family 1 G-protein coupled receptor that stimulates the GTPase activity of Gi2. Receptor for the chemotactic and inflammatory complement factor C5a. Stimulates chemotaxis, granule enzyme release and superoxide anion production. Phosphorylated in response to C5a or after stimulation of cells with phorbol esters. Expressed on monocytes, granulocytes, dendritic cells, astrocytes and microglia.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 19q13.3-q13.4

Cellular Component: apical part of cell; basolateral plasma membrane; integral to plasma membrane; plasma membrane

Molecular Function: complement component C5a receptor activity; G-protein coupled receptor activity

Biological Process: activation of MAPK activity; cellular defense response; chemotaxis; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); immune response; inflammatory response; leukocyte migration; mRNA transcription from RNA polymerase II promoter; phospholipase C activation; positive regulation of epithelial cell proliferation; regulation of complement activation; sensory perception of chemical stimulus; signal transduction

Research Articles on CD88

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Product Notes

The CD88 c5ar1 (Catalog #AAA9416836) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD88 (Phospho-Ser327) Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD88 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000. Researchers should empirically determine the suitability of the CD88 c5ar1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD88, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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