Rabbit anti-Mouse CD62P Polyclonal Antibody | anti-CD62P antibody
Anti-Mouse CD62P DyLight 550 conjugated Antibody
Gene Names
Selp; Grmp; CD62P; LECAM3; PADGEM; GMP-140
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay
Purity
Immunogen Affinity Purified
Synonyms
CD62P; Polyclonal Antibody; Anti-Mouse CD62P DyLight 550 conjugated Antibody; Rabbit IgG Polyclonal Anti-Mouse CD62P Antibody DyLight 550 Conjugated; Flow Validated; P-selectin; CD62 antigen-like family member P; Granule membrane protein 140; GMP-140; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; Platelet activation dependent granule-external membrane protein; PADGEM; Selp; Grmp; Selectin; platelet; anti-CD62P antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
No cross reactivity with other proteins.
Purity/Purification
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
768
Applicable Applications for anti-CD62P antibody
Flow Cytometry (FC/FACS)
Application Notes
FC/FACS: 1-3ug/1x106 cells
Immunogen
E Coli-derived mouse CD62P recombinant protein (Position: W42-A267).
Preparation and Storage
Store at 2-8 degree C for one year. Protect from light. Do not freeze.
Related Product Information for anti-CD62P antibody
CD62P is also known as SELP or P-selectin. This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.
References
1. Gremmel T, et al. Impact of diabetes on platelet activation in different manifestations of atherosclerosis. Swiss Med Wkly, 2013 May 28. 2. Kutlar A, et al. Cellular adhesion and the endothelium: P-selectin. Hematol Oncol Clin North Am, 2014 Apr.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
83,099 Da
NCBI Official Full Name
P-selectin
NCBI Official Synonym Full Names
selectin, platelet
NCBI Official Symbol
Selp
NCBI Official Synonym Symbols
Grmp; CD62P; LECAM3; PADGEM; GMP-140
NCBI Protein Information
P-selectin
UniProt Protein Name
P-selectin
UniProt Gene Name
Selp
UniProt Synonym Gene Names
Grmp; GMP-140; LECAM3; PADGEM
Uniprot Description
Ca2+-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG.
Research Articles on CD62P
Similar Products
Product Notes
The CD62P selp (Catalog #AAA1751320) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse CD62P DyLight 550 conjugated Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD62P can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). FC/FACS: 1-3ug/1x106 cells. Researchers should empirically determine the suitability of the CD62P selp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD62P, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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