Immunohistochemistry (IHC)
(Immunochemical staining of mouse MSR1 in mouse liver with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).Positive staining was localized to hepatic sinusoid.)
Rabbit anti-Mouse CD204/MSR1 Polyclonal Antibody | anti-MSR1 antibody
Anti-CD204/MSR1 Antibody, Rabbit Polyclonal
Reactivity
Mouse
Applications
ELISA, Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
CD204/MSR1; Polyclonal Antibody; Anti-CD204/MSR1 Antibody; Rabbit Polyclonal; MSR1/CD204 Antibody; Rabbit PAb; Antigen Affinity Purified; macrophage scavenger receptor 1; Anti-MRS-A Antibody; Anti-MSR Antibody; Anti-MSR-A Antibody; Anti-Scara1 Antibody; Anti-Scvr Antibody; Anti-SR-AI Antibody; Anti-SR-AII Antibody; anti-MSR1 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Mouse MSR1/CD204
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-MSR1 antibody
ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
ELISA: 1:5000-1:10,000
IHC-P: 1:500-1:2000
IHC-P: 1:500-1:2000
Immunogen
Recombinant Mouse MSR1/CD204 protein
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with purified, recombinant Mouse MSR1/CD204 (rM MSR1/CD204). MSR1/CD204 specific IgG was purified by Mouse MSR1/CD204 affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of mouse MSR1 in mouse liver with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).Positive staining was localized to hepatic sinusoid.)
Immunohistochemistry (IHC)
(Immunochemical staining of mouse MSR1 in mouse liver with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).Positive staining was localized to hepatic sinusoid.)
Related Product Information for anti-MSR1 antibody
Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD24, MSR1, and SCARA1, is a single-pass type II membrane protein that contains one collagen-like domain and one SRCR domain. Macrophages are distributed in all peripheral tissues and play a critical role in the first line of the innate immune defenses against bacterial infection by phagocytosis of bacterial pathogens through the macrophage scavenger receptor 1 (MSR1). MSR1/SCARA1 is one of the membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low-density lipoproteins (LDL). MSR1/SCARA1 is also involved in chronic inflammation which is a risk factor for prostate cancer. MSR1 1 gene was identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer.
References
Wang L. et al., 2003, Nat Genet. 35 (2): 128-9. Chen Y.C. et al., 2008, Cancer Epidemiol Biomarkers Prev. 17 (4): 1001-3. Shirato K. et al., 2009, Pflugers Arch. 459 (1): 93-103. Sun J. et al., 2006, Prostate. 66 (7): 728-37.
NCBI and Uniprot Product Information
Protein Family
Similar Products
Product Notes
The MSR1 (Catalog #AAA8111049) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD204/MSR1 Antibody, Rabbit Polyclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD204/MSR1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P). ELISA: 1:5000-1:10,000 IHC-P: 1:500-1:2000. Researchers should empirically determine the suitability of the MSR1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD204/MSR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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