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Western Blot (WB) (Western Blot analysis of CD200R1 expression in transfected 293T cell line by CD200R1 polyclonal antibody. Lane 1: CD200R1 transfected lysate (39kD). Lane 2: Non-transfected lysate.)

Rabbit anti-Human CD200R1 Polyclonal Antibody | anti-CD200R1 antibody

CD200R1 (Cell Surface Glycoprotein CD200 Receptor 1, CD200 Cell Surface Glycoprotein Receptor, Cell Surface Glycoprotein OX2 Receptor 1, CD200R, CRTR2, MOX2R, OX2R, UNQ2522/PRO6015) (FITC)

Gene Names
CD200R1; OX2R; MOX2R; CD200R; HCRTR2
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
CD200R1; Polyclonal Antibody; CD200R1 (Cell Surface Glycoprotein CD200 Receptor 1; CD200 Cell Surface Glycoprotein Receptor; Cell Surface Glycoprotein OX2 Receptor 1; CD200R; CRTR2; MOX2R; OX2R; UNQ2522/PRO6015) (FITC); anti-CD200R1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human CD200R1.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Applicable Applications for anti-CD200R1 antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length human CD200R1, aa1-348 (NP_620161.1).
Immunogen Sequence
MLCPWRTANLGLLLILTIFLVAEAEGAAQPNNSLMLQTSKENHALASSSLCMDEKQITQNYSKVLAEVNTSWPVKMATNAVLCCPPIALRNLIIITWEIILRGQPSCTKAYKKETNETKETNCTDERITWVSRPDQNSDLQIRTVAITHDGYYRCIMVTPDGNFHRGYHLQVLVTPEVTLFQNRNRTAVCKAVAGKPAAHISWIPEGDCATKQEYWSNGTVTVKSTCHWEVHNVSTVTCHVSHLTGNKSLYIELLPVPGAKKSAKLYIPYIILTIIILTIVGFIWLLKVNGCRKYKLNKTESTPVVEEDEMQPYASYTEKNNPLYDTTNKVKASEALQSEVDTDLHTL
Conjugate
FITC
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of CD200R1 expression in transfected 293T cell line by CD200R1 polyclonal antibody. Lane 1: CD200R1 transfected lysate (39kD). Lane 2: Non-transfected lysate.)

Western Blot (WB) (Western Blot analysis of CD200R1 expression in transfected 293T cell line by CD200R1 polyclonal antibody. Lane 1: CD200R1 transfected lysate (39kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-CD200R1 antibody
CD200 R1, also known as OX2 receptor, is one of four known members of the mouse CD200 R family. CD200 receptors belong to the immunoglobulin superfamily. Mouse CD200 R1 is a type I transmembrane protein with a cytoplasmic region that contains a PTB-signaling motif. Engagement of CD200 and CD200 R1 has been shown to elicit an inhibitory signal. The extracellular domain of mouse CD200 R1 shares 43% and 72% aa sequence homology with the corresponding regions of human and rat CD200 R1, respectively.
Product Categories/Family for anti-CD200R1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
36,620 Da
NCBI Official Full Name
cell surface glycoprotein CD200 receptor 1 isoform a
NCBI Official Synonym Full Names
CD200 receptor 1
NCBI Official Symbol
CD200R1
NCBI Official Synonym Symbols
OX2R; MOX2R; CD200R; HCRTR2
NCBI Protein Information
cell surface glycoprotein CD200 receptor 1; MOX2 receptor; CD200 cell surface glycoprotein receptor; cell surface glycoprotein OX2 receptor 1; cell surface glycoprotein receptor CD200
UniProt Protein Name
Cell surface glycoprotein CD200 receptor 1
UniProt Gene Name
CD200R1
UniProt Synonym Gene Names
CD200R; CRTR2; MOX2R; OX2R
UniProt Entry Name
MO2R1_HUMAN

NCBI Description

This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Uniprot Description

CD200R: Receptor for the CD200/OX2 cell surface glycoprotein. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200. Belongs to the CD200R family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 3q13.2

Cellular Component: integral to membrane; extracellular region; plasma membrane; receptor complex

Molecular Function: protein binding

Biological Process: regulation of immune response; viral reproduction

Research Articles on CD200R1

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Product Notes

The CD200R1 cd200r1 (Catalog #AAA6372919) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD200R1 (Cell Surface Glycoprotein CD200 Receptor 1, CD200 Cell Surface Glycoprotein Receptor, Cell Surface Glycoprotein OX2 Receptor 1, CD200R, CRTR2, MOX2R, OX2R, UNQ2522/PRO6015) (FITC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD200R1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CD200R1 cd200r1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD200R1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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