Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded mouse Inflammatory spleen using CD163 Polyclonal Antibody at dilution of 1:300.)
Rabbit anti-Mouse, Rat CD163 Polyclonal Antibody | anti-CD163 antibody
CD163 Polyclonal Antibody
Gene Names
Cd163; CD163v2; CD163v3
Reactivity
Mouse, Rat
Applications
Immunohistochemistry
Purity
Affinity Purification
Synonyms
CD163; Polyclonal Antibody; CD163 Polyclonal Antibody; M130; MM130; SCARI1; CD163 molecule; anti-CD163 antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 100 ug/ml BSA and 50% glycerol.
Concentration
340 mug/mL (varies by lot)
Sequence Length
1,159
Applicable Applications for anti-CD163 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:200-1:1000
Note: Centrifuge before opening to ensure complete recovery of vial contents.
Note: Centrifuge before opening to ensure complete recovery of vial contents.
Immunogen
Recombinant protein corresponding to Mouse CD163
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded mouse Inflammatory spleen using CD163 Polyclonal Antibody at dilution of 1:300.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded mouse Inflammatory spleen using CD163 Polyclonal Antibody at dilution of 1:300.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded rat Inflammatory spleen using CD163 Polyclonal Antibody at dilution of 1:300.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded rat Inflammatory spleen using CD163 Polyclonal Antibody at dilution of 1:300.)
Related Product Information for anti-CD163 antibody
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Product Categories/Family for anti-CD163 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
scavenger receptor cysteine-rich type 1 protein M130 isoform 2
NCBI Official Synonym Full Names
CD163 antigen
NCBI Official Symbol
Cd163
NCBI Official Synonym Symbols
CD163v2; CD163v3
NCBI Protein Information
scavenger receptor cysteine-rich type 1 protein M130
UniProt Protein Name
Scavenger receptor cysteine-rich type 1 protein M130
Protein Family
UniProt Gene Name
Cd163
UniProt Synonym Gene Names
M130; sCD163
Uniprot Description
Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 ().
Research Articles on CD163
Similar Products
Product Notes
The CD163 cd163 (Catalog #AAA2556324) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD163 Polyclonal Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD163 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:200-1:1000 Note: Centrifuge before opening to ensure complete recovery of vial contents. Researchers should empirically determine the suitability of the CD163 cd163 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD163, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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