Immunohistochemistry (IHC)
(Sample Type: Human nasal epithelialApplication: IHCSpecies+tissue/cell type:Human nasal epithelial cellsPrimary antibody dilution: 1:1000Secondary antibody: Goat anti-rabbit Alexa Fluor 546Secondary antibody dilution:1:1000)
Rabbit CD151 Polyclonal Antibody | anti-CD151 antibody
CD151 antibody - C-terminal region
Immunohistochemistry (IHC)
(Sample Type: Human nasal epithelialApplication: IHCSpecies+tissue/cell type:Human nasal epithelial cellsPrimary antibody dilution: 1:1000Secondary antibody: Goat anti-rabbit Alexa Fluor 546Secondary antibody dilution:1:1000)
Immunohistochemistry (IHC)
(Sample Type: Human nasal epithelialApplication: IHCSpecies+tissue/cell type:Human nasal epithelial cellsPrimary antibody dilution: 1:1000Secondary antibody: Goat anti-rabbit Alexa Fluor 546Secondary antibody dilution:1:1000)
Western Blot (WB)
(WB Suggested Anti-CD151 AntibodyTitration: 1.0 ug/mlPositive Control: A549 Whole CellCD151 is supported by BioGPS gene expression data to be expressed in A549)
Western Blot (WB)
(WB Suggested Anti-CD151 AntibodyTitration: 1.0 ug/mlPositive Control: A549 Whole CellCD151 is supported by BioGPS gene expression data to be expressed in A549)
Target Description: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
CD151: Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. Defects in CD151 are the cause of nephropathy with pretibial epidermolysis bullosa and deafness (NPEBD). NPEBD is characterized by the association of hereditary nephritis, epidermolysis bullosa, deafness, and beta-thalassemia minor. Belongs to the tetraspanin (TM4SF) family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 11p15.5
Cellular Component: focal adhesion; membrane; integral to plasma membrane; plasma membrane; cytosol
Molecular Function: integrin binding; protein binding
Biological Process: T cell proliferation; extracellular matrix organization and biogenesis; cell migration; hemidesmosome assembly; cell adhesion
Disease: Raph Blood Group System; Nephropathy With Pretibial Epidermolysis Bullosa And Deafness
Research Articles on CD151
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Product Notes
The CD151 cd151 (Catalog #AAA3216055) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD151 antibody - C-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD151 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the CD151 cd151 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: HCCGSNNSQD WRDSEWIRSQ EAGGRVVPDS CCKTVVALCG QRDHASNIYK. It is sometimes possible for the material contained within the vial of "CD151, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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