Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CCNY Polyclonal Antibody at dilution of 1:35(×200))
Rabbit anti-Human, Mouse CCNY Polyclonal Antibody | anti-CCNY antibody
CCNY Polyclonal Antibody
ELISA: 1:5000-1:10000
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CCNY Polyclonal Antibody at dilution of 1:35(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CCNY Polyclonal Antibody at dilution of 1:35(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using CCNY Polyclonal Antibody at dilution of 1:35(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using CCNY Polyclonal Antibody at dilution of 1:35(×200))
NCBI and Uniprot Product Information
NCBI Description
Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2; MIM 116940) (Li et al., 2009 [PubMed 18060517]).[supplied by OMIM, May 2009]
Uniprot Description
Function: Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription. Ref.1 Ref.2 Ref.14 Ref.18
Subunit structure: Interacts with CDK14, CDK16 and LRP6. Ref.1 Ref.14 Ref.18
Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side Ref.1 Ref.2 Ref.14 Ref.18. Isoform 3: Nucleus Ref.1 Ref.2 Ref.14 Ref.18.
Tissue specificity: Widely expressed. Ref.2
Developmental stage: Enriched at G2/M. Ref.14
Post-translational modification: Ubiquitinated; leading to its degradation. Ref.14
Sequence similarities: Belongs to the cyclin family. Cyclin Y subfamily.Contains 1 cyclin N-terminal domain.
Sequence caution: The sequence AAH69224.1 differs from that shown. Reason: Erroneous initiation.
Research Articles on CCNY
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Product Notes
The CCNY ccny (Catalog #AAA2561667) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCNY Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CCNY can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:25-1:100 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the CCNY ccny for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCNY, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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