Rabbit anti-Human CCDC62 Polyclonal Antibody | anti-CCDC62 antibody
CCDC62, CT (CCDC62, Coiled-coil domain-containing protein 62, Protein TSP-NY, Protein aaa) (PE)
Gene Names
CCDC62; CT109; ERAP75; TSP-NY
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
CCDC62; Polyclonal Antibody; CT (CCDC62; Coiled-coil domain-containing protein 62; Protein TSP-NY; Protein aaa) (PE); Protein aaa; anti-CCDC62 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Applicable Applications for anti-CCDC62 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes
IHC: 1:50-100
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
CCDC62 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 654-684 amino acids from the C-terminal region of human CCDC62.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(Western blot analysis of CCDC62 Antibody (C-term) in NCI-H460 cell line lysates (35ug/lane).CCDC62 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(CCDC62 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CCDC62 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-CCDC62 antibody
The function of this protein has not been specifically defined.
Product Categories/Family for anti-CCDC62 antibody
References
Domae, S., et al. Int. J. Cancer 124(10):2347-2352(2009). Chen, M., et al. Carcinogenesis 30(5):841-850(2009). Chen, M., et al. Prostate 68(12):1273-1282(2008).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
77,748 Da
NCBI Official Full Name
coiled-coil domain-containing protein 62
NCBI Official Synonym Full Names
coiled-coil domain containing 62
NCBI Official Symbol
CCDC62
NCBI Official Synonym Symbols
CT109; ERAP75; TSP-NY
NCBI Protein Information
coiled-coil domain-containing protein 62; aaa-protein; cancer/testis antigen 109; testis-specific protein TSP-NY; coiled-coil domain-containing protein 60
UniProt Protein Name
Coiled-coil domain-containing protein 62
Protein Family
UniProt Gene Name
CCDC62
UniProt Entry Name
CCD62_HUMAN
Uniprot Description
CCDC62: Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Cancer Testis Antigen (CTA)
Chromosomal Location of Human Ortholog: 12q24.31
Cellular Component: nucleoplasm; cytoplasm; plasma membrane; nucleus
Molecular Function: ligand-dependent nuclear receptor transcription coactivator activity; estrogen receptor binding
Biological Process: positive regulation of transcription from RNA polymerase II promoter
