Western Blot (WB)
(CCDC39 Antibody (C-term) western blot analysis in CHO cell line lysates (35ug/lane).This demonstrates the CCDC39 antibody detected the CCDC39 protein (arrow).)
Rabbit CCDC39 Polyclonal Antibody | anti-CCDC39 antibody
CCDC39 Antibody (C-term)
Western Blot (WB)
(CCDC39 Antibody (C-term) western blot analysis in CHO cell line lysates (35ug/lane).This demonstrates the CCDC39 antibody detected the CCDC39 protein (arrow).)
Western Blot (WB)
(CCDC39 Antibody (C-term) western blot analysis in CHO cell line lysates (35ug/lane).This demonstrates the CCDC39 antibody detected the CCDC39 protein (arrow).)
Western Blot (WB)
(CCDC39 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the CCDC39 antibody detected the CCDC39 protein (arrow).)
Western Blot (WB)
(CCDC39 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the CCDC39 antibody detected the CCDC39 protein (arrow).)
Harrington, J.J., et al. Nat. Biotechnol. 19(5):440-445(2001)
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is involved in the motility of cilia and flagella. The encoded protein is essential for the assembly of dynein regulatory and inner dynein arm complexes, which regulate ciliary beat. Defects in this gene are a cause of primary ciliary dyskinesia type 14 (CILD14). [provided by RefSeq, Jul 2011]
Uniprot Description
CCDC39: Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly. Defects in CCDC39 are the cause of primary ciliary dyskinesia type 14 (CILD14). A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome. Belongs to the CCDC39 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 3q26.33
Cellular Component: cytoskeleton; axoneme
Biological Process: heart looping; lung development
Disease: Ciliary Dyskinesia, Primary, 14
Research Articles on CCDC39
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Product Notes
The CCDC39 ccdc39 (Catalog #AAA9210863) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 770-798. The CCDC39 Antibody (C-term) reacts with Human, hamster, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CCDC39 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the CCDC39 ccdc39 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCDC39, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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