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Western Blot (WB) (CCBL1 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the CCBL1 antibody detected the CCBL1 protein (arrow).)

Rabbit anti-Human CCBL1 Polyclonal Antibody | anti-CCBL1 antibody

CCBL1, CT (CCBL1, Kynurenine-oxoglutarate transaminase 1, Cysteine-S-conjugate beta-lyase, Glutamine transaminase K, Glutamine-phenylpyruvate transaminase, Kynurenine aminotransferase I, Kynurenine-oxoglutarate transaminase I)

Gene Names
CCBL1; GTK; KAT1; KATI
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
CCBL1; Polyclonal Antibody; CT (CCBL1; Kynurenine-oxoglutarate transaminase 1; Cysteine-S-conjugate beta-lyase; Glutamine transaminase K; Glutamine-phenylpyruvate transaminase; Kynurenine aminotransferase I; Kynurenine-oxoglutarate transaminase I); Anti -CCBL1; anti-CCBL1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Applicable Applications for anti-CCBL1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunogen
CCBL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-355 amino acids from the C-terminal region of human CCBL1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(CCBL1 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the CCBL1 antibody detected the CCBL1 protein (arrow).)

Western Blot (WB) (CCBL1 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the CCBL1 antibody detected the CCBL1 protein (arrow).)
Related Product Information for anti-CCBL1 antibody
This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.
Product Categories/Family for anti-CCBL1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
883
UniProt Accession #
Molecular Weight
47,875 Da
NCBI Official Full Name
CCBL1 protein
NCBI Official Synonym Full Names
cysteine conjugate-beta lyase, cytoplasmic
NCBI Official Symbol
CCBL1
NCBI Official Synonym Symbols
GTK; KAT1; KATI
NCBI Protein Information
kynurenine--oxoglutarate transaminase 1; beta-lysase, kidney; glutamine transaminase K; kyneurenine aminotransferase; kynurenine aminotransferase I; cysteine-S-conjugate beta-lyase; glutamine--phenylpyruvate transaminase; kynurenine--oxoglutarate transaminase I; glutamine-phenylpyruvate aminotransferase; cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase)
UniProt Protein Name
Kynurenine--oxoglutarate transaminase 1
UniProt Gene Name
CCBL1
UniProt Synonym Gene Names
GTK; KATI
UniProt Entry Name
KAT1_HUMAN

NCBI Description

This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

CCBL1: Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta- elimination of S-conjugates and Se-conjugates of L- (seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.6.1.64; Transferase; EC 4.4.1.13; EC 2.6.1.7; Lyase

Chromosomal Location of Human Ortholog: 9q34.11

Cellular Component: nucleoplasm; cytoplasm; cytosol

Molecular Function: cysteine-S-conjugate beta-lyase activity; protein homodimerization activity; glutamine-pyruvate transaminase activity; kynurenine-oxoglutarate transaminase activity; glutamine-phenylpyruvate transaminase activity; transaminase activity; phenylalanine(histidine) transaminase activity; pyridoxal phosphate binding

Biological Process: L-phenylalanine catabolic process; amino acid biosynthetic process; tryptophan catabolic process; amino acid derivative metabolic process

Research Articles on CCBL1

Similar Products

Product Notes

The CCBL1 ccbl1 (Catalog #AAA6008558) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCBL1, CT (CCBL1, Kynurenine-oxoglutarate transaminase 1, Cysteine-S-conjugate beta-lyase, Glutamine transaminase K, Glutamine-phenylpyruvate transaminase, Kynurenine aminotransferase I, Kynurenine-oxoglutarate transaminase I) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CCBL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the CCBL1 ccbl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCBL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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