Rabbit CBX5 Polyclonal Antibody | anti-CBX5 antibody

CBX5 Rabbit Polyclonal

Cat. Num. AAA767564

• Gene Names: CBX5; HP1; HP1A; HEL25
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: CBX5; Polyclonal Antibody; CBX5 Rabbit Polyclonal; anti-CBX5 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 191

• Applicable Applications for anti-CBX5 antibody: ELISA (EIA), Western Blot (WB)
• Immunogen: Chromobox homolog 5 (HP1 alpha homolog, Drosophila)
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human brain using MBS767564 (CBX5 antibody) at dilution of 1:100)

Western Blot (WB)

(HeLa cells were subjected to SDS PAGE followed by western blot with MBS767564 (CBX5 antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

• NCBI GI #: 48146953
• NCBI GeneID: 23468
• UniProt Accession #: Q6I9T7; P45973
• Molecular Weight: 22,167 Da
• NCBI Official Full Name: CBX5
• NCBI Official Synonym Full Names: chromobox 5
• NCBI Official Symbol: CBX5
• NCBI Official Synonym Symbols: HP1; HP1A; HEL25
• NCBI Protein Information: chromobox protein homolog 5
• UniProt Protein Name: CBX5 protein
• Protein Family: Chromobox protein
• UniProt Gene Name: CBX5
• UniProt Entry Name: Q6I9T7_HUMAN

NCBI Description

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]