Rabbit CBS Polyclonal Antibody | anti-CBS antibody
CBS
Gene Names
CBS; CBSL; HIP4
Reactivity
HumanPredicted: Rat, Mouse
Applications
ELISA, Western Blot
Purity
Purified By Antigen Affinity Column
Synonyms
CBS; Polyclonal Antibody; HIP4; anti-CBS antibody
Host
Rabbit
Reactivity
Human
Predicted: Rat, Mouse
Predicted: Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Antigen Affinity Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
2369
Applicable Applications for anti-CBS antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:10000-80000
WB: 1:200-1000
WB: 1:200-1000
Immunogen
Recombinant fragment corresponding to 87-239aa of human CBS.
Cellular Localization
Cytoplasm, Nucleus
Related Product Information for anti-CBS antibody
Homo sapiens cystathionine-beta-synthase (CBS), mRNA.
References
Longhi RC, Fleisher LD, Tallan HH, et al. Cystathionine beta-synthase deficiency: a qualitative abnormality of the deficient enzyme modified by vitamin B6 therapy. Pediatr Res. 11 (2):100-103 (1977)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
61KD
NCBI Official Full Name
Homo sapiens cystathionine-beta-synthase, mRNA
NCBI Official Synonym Full Names
cystathionine beta-synthase
NCBI Official Symbol
CBS
NCBI Official Synonym Symbols
CBSL; HIP4
NCBI Protein Information
cystathionine beta-synthase
Protein Family
NCBI Description
The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]
Research Articles on CBS
Similar Products
Product Notes
The CBS (Catalog #AAA8562241) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CBS reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CBS can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:10000-80000 WB: 1:200-1000. Researchers should empirically determine the suitability of the CBS for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CBS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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