Western Blot (WB)
(Western blot analysis of CBR4 expression in Jurkat (A), MCF7 (B) whole cell lysates.)
Rabbit anti-Human, Rat CBR4 Polyclonal Antibody | anti-CBR4 antibody
Anti-CBR4 Antibody
Gene Names
CBR4; SDR45C1
Reactivity
Human, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Purified by immunogen affinity chromatography
Synonyms
CBR4; Polyclonal Antibody; Anti-CBR4 Antibody; Carbonyl reductase family member 4; 3-oxoacyl-[acyl-carrier-protein] reductase; Quinone reductase CBR4; anti-CBR4 antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of CBR4 protein.
Purity/Purification
Purified by immunogen affinity chromatography
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Sequence Length
237
Applicable Applications for anti-CBR4 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1/500 - 1/2000
IHC: 1/50 - 1/200
IHC: 1/50 - 1/200
Immunogen
Recombinant full length protein of human CBR4
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of CBR4 expression in Jurkat (A), MCF7 (B) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of CBR4 expression in Jurkat (A), MCF7 (B) whole cell lysates.)
Related Product Information for anti-CBR4 antibody
Rabbit polyclonal antibody to CBR4
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
18,837 Da
NCBI Official Full Name
carbonyl reductase family member 4
NCBI Official Synonym Full Names
carbonyl reductase 4
NCBI Official Symbol
CBR4
NCBI Official Synonym Symbols
SDR45C1
NCBI Protein Information
carbonyl reductase family member 4
UniProt Protein Name
Carbonyl reductase family member 4
Protein Family
UniProt Gene Name
CBR4
UniProt Synonym Gene Names
SDR45C1; KAR beta subunit
Uniprot Description
The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis (PubMed:19571038, PubMed:25203508). Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD (PubMed:25203508). The homotetramer has NADPH-dependent quinone reductase activity (PubMed:19000905). Both homotetramer and the heterotetramer have broad substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro) (PubMed:19000905, PubMed:19571038, PubMed:25203508).
Research Articles on CBR4
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Product Notes
The CBR4 cbr4 (Catalog #AAA8292170) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CBR4 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CBR4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1/500 - 1/2000 IHC: 1/50 - 1/200. Researchers should empirically determine the suitability of the CBR4 cbr4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CBR4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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