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Immunohistochemistry (IHC) (Anti-CBLN1 / Precerebellin antibody IHC of mouse kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Rabbit CBLN1 / Cerebellin 1 Polyclonal Antibody | anti-CBLN1 antibody

Rabbit Polyclonal to Human CBLN1 / Cerebellin 1

Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
CBLN1 / Cerebellin 1; Polyclonal Antibody; Rabbit Polyclonal to Human CBLN1 / Cerebellin 1; Anti-CBLN1 / Cerebellin 1 Antibody IHC-plus; CBLN1; CLN1; Cerebellin; Cerebellin 1 precursor; Precerebellin; Cerebellin-1; Human CBLN1; Cerebellin 1; anti-CBLN1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
15 amino acid peptide from the middle of human precerebellin
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.02% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
193
Applicable Applications for anti-CBLN1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes
IHC-P (10 ug/ml), WB (2 - 4 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues and mouse tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with...
Target Species
Human
Immunogen Description
Synthetic peptide from human CBLN1.
Immunogen Type
Synthetic peptide
Immunogen
CBLN1 / Cerebellin 1 antibody was raised against synthetic peptide from human CBLN1.
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-CBLN1 / Precerebellin antibody IHC of mouse kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC) (Anti-CBLN1 / Precerebellin antibody IHC of mouse kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC)

(Anti-CBLN1 / Precerebellin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC) (Anti-CBLN1 / Precerebellin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC)

(Anti-CBLN1 / Precerebellin antibody IHC of mouse small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC) (Anti-CBLN1 / Precerebellin antibody IHC of mouse small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Western Blot (WB)

(Western blot of precerebellin in mouse cerebellum lysate with at (A) 2 and (B) 4 ug/ml.)

Western Blot (WB) (Western blot of precerebellin in mouse cerebellum lysate with at (A) 2 and (B) 4 ug/ml.)
Related Product Information for anti-CBLN1 antibody
Cerebellin (CBLN1) encodes a cerebellum-specific precursor protein, precerebellin, with similarity to the globular (non-collagen-like) domain of complement component C1qB. Precerebellin is processed to give rise to several derivatives, including the hexadecapeptide, cerebellin, which is highly enriched in postsynaptic structures of Purkinje cells. Cerebellin has also been found in human and rat adrenals, where it has been shown to enhance the secretory activity of this gland.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
869
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
21,097 Da
NCBI Official Full Name
cerebellin-1
NCBI Official Synonym Full Names
cerebellin 1 precursor
NCBI Official Symbol
CBLN1
NCBI Protein Information
cerebellin-1; precerebellin
UniProt Protein Name
Cerebellin-1
Protein Family
UniProt Gene Name
CBLN1
UniProt Synonym Gene Names
CER
UniProt Entry Name
CBLN1_HUMAN

NCBI Description

This gene encodes a cerebellum-specific precursor protein, precerebellin, with similarity to the globular (non-collagen-like) domain of complement component C1qB. Precerebellin is processed to give rise to several derivatives, including the hexadecapeptide, cerebellin, which is highly enriched in postsynaptic structures of Purkinje cells. Cerebellin has also been found in human and rat adrenals, where it has been shown to enhance the secretory activity of this gland. [provided by RefSeq, Aug 2008]

Uniprot Description

CBLN1: Cerebellin-1 is required for synapse integrity and synaptic plasticity. Required for the ER export and secretion of CBLN3.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16q12.1

Cellular Component: postsynaptic membrane; extracellular region; cell junction

Molecular Function: protein homodimerization activity

Biological Process: heterophilic cell adhesion; synaptic transmission; nervous system development; positive regulation of synaptogenesis; protein secretion; cerebellar granule cell differentiation

Research Articles on CBLN1

Similar Products

Product Notes

The CBLN1 cbln1 (Catalog #AAA240452) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human CBLN1 / Cerebellin 1 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CBLN1 / Cerebellin 1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB). IHC-P (10 ug/ml), WB (2 - 4 ug/ml) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues and mouse tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with.. Researchers should empirically determine the suitability of the CBLN1 cbln1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CBLN1 / Cerebellin 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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