Western Blot (WB)
(Western Blot: Sample: Lane1: Human SW480 Cells; Lane2: Porcine Large Intestine Tissue; Lane3: Porcine Small Intestine Tissue.)
Rabbit anti-Human Caudal Type Homeobox Transcription Factor 2 Polyclonal Antibody | anti-CDX2 antibody
Caudal Type Homeobox Transcription Factor 2 (CDX2) Polyclonal Antibody
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Enzyme-linked Immunosorbent Assay: 1:100-200
Usage: 10uL per well when 3,3'-Diaminobenzidine(DAB) as the substrate.
5uL per well when used in enhanced chemilumescent (ECL).
Note: The quality control is specifically manufactured as the positive control.Not used for other purposes.
Loading Buffer: 100mM Tris(pH8.8), 2% SDS, 200mM NaCl, 50% glycerol,BPB 0.01%, NaN3 0.02%.
Western Blot (WB)
(Western Blot: Sample: Lane1: Human SW480 Cells; Lane2: Porcine Large Intestine Tissue; Lane3: Porcine Small Intestine Tissue.)
Western Blot (WB)
(Western Blot: Sample: Lane1: Human SW480 Cells; Lane2: Porcine Large Intestine Tissue; Lane3: Porcine Small Intestine Tissue.)
Western Blot (WB)
(Western Blot: Sample: Recombinant CDX2, Human.)
Western Blot (WB)
(Western Blot: Sample: Recombinant CDX2, Human.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Human Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Human Tissue))
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012]
Uniprot Description
CDX2: Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Belongs to the Caudal homeobox family.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 13q12.2
Cellular Component: condensed nuclear chromosome; nucleoplasm; nucleus; protein complex; transcriptional repressor complex
Molecular Function: DNA binding transcription factor activity; transcription corepressor activity
Biological Process: anterior/posterior axis specification; blood vessel development; cell differentiation; endosome to lysosome transport; establishment or maintenance of epithelial cell apical/basal polarity; negative regulation of transcription from RNA polymerase II promoter; organ morphogenesis; positive regulation of cell differentiation; positive regulation of cell proliferation; positive regulation of transcription, DNA-templated; regulation of somitogenesis; somatic stem cell maintenance; transcription from RNA polymerase II promoter; trophectodermal cell differentiation
Research Articles on CDX2
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Product Notes
The CDX2 cdx2 (Catalog #AAA2032861) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Caudal Type Homeobox Transcription Factor 2 (CDX2) Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Caudal Type Homeobox Transcription Factor 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western Blot: 1:50-400 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the CDX2 cdx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Caudal Type Homeobox Transcription Factor 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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