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Western Blot (WB) (Western blot analysis of extracts from 293 cells and COS-7 cells treated with etoposide (25uM, 1hour), and HeLa cells treated with etoposide (25uM, 24hours) using CATL2 antibody)

Rabbit CATL2 Polyclonal Antibody | anti-CATL2 antibody

CATL2 antibody

Gene Names
CTSV; CTSU; CATL2; CTSL2
Applications
Western Blot, ELISA
Synonyms
CATL2; Polyclonal Antibody; CATL2 antibody; Polyclonal CATL2; Anti-CATL2; Cathepsin L2 [Precursor]; EC 3.4.22.43; Cathepsin V; Cathepsin U; CTSL2; CTSU; CTSV; UNQ268/PRO305; anti-CATL2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
CATL2 antibody detects endogenous levels of fragment of activated CATL2 resulting from cleavage adjacent to Leu114
Form/Format
Purified IgG in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
334
Applicable Applications for anti-CATL2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:1000
ELISA: 1:20000
Biological Significance
CATL2 is a lysosomal cysteine proteinase that may play an important role in corneal physiology.
Immunogen
CATL2 antibody was raised in Rabbit using a synthesized peptide derived from human CATL2 as the immunogen
Preparation and Storage
Store at -20 degree C in small aliquots. Avoid repeated freeze-thaw cycles

Western Blot (WB)

(Western blot analysis of extracts from 293 cells and COS-7 cells treated with etoposide (25uM, 1hour), and HeLa cells treated with etoposide (25uM, 24hours) using CATL2 antibody)

Western Blot (WB) (Western blot analysis of extracts from 293 cells and COS-7 cells treated with etoposide (25uM, 1hour), and HeLa cells treated with etoposide (25uM, 24hours) using CATL2 antibody)
Related Product Information for anti-CATL2 antibody
Rabbit polyclonal CATL2 antibody
Product Categories/Family for anti-CATL2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
37,329 Da
NCBI Official Full Name
cathepsin L2 preproprotein
NCBI Official Synonym Full Names
cathepsin V
NCBI Official Symbol
CTSV
NCBI Official Synonym Symbols
CTSU; CATL2; CTSL2
NCBI Protein Information
cathepsin L2
UniProt Protein Name
Cathepsin L2
UniProt Gene Name
CTSV
UniProt Synonym Gene Names
CATL2; CTSL2; CTSU
UniProt Entry Name
CATL2_HUMAN

NCBI Description

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2011]

Uniprot Description

CTSL2: Cysteine protease. May have an important role in corneal physiology. Belongs to the peptidase C1 family.

Protein type: Protease; Secreted, signal peptide; Secreted; EC 3.4.22.15

Chromosomal Location of Human Ortholog: 9q22.2

Cellular Component: lysosomal lumen; extracellular space; neuron projection; microvillus; apical part of cell; nucleolus; extracellular region; perikaryon; secretory granule; external side of plasma membrane

Molecular Function: protein binding; histone binding; cysteine-type endopeptidase activity; protein complex binding; kininogen binding; cysteine-type carboxypeptidase activity; aminopeptidase activity; peptide binding; cysteine-type peptidase activity

Biological Process: extracellular matrix organization and biogenesis; hair follicle morphogenesis; response to glucocorticoid stimulus; Sertoli cell differentiation; multicellular organismal aging; antigen processing and presentation of exogenous peptide antigen via MHC class II; decidualization; cellular response to starvation; proteolysis; extracellular matrix disassembly; protein autoprocessing; response to glucose stimulus; autophagic cell death; spermatogenesis; nerve development

Research Articles on CATL2

Similar Products

Product Notes

The CATL2 ctsv (Catalog #AAA5300141) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CATL2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:1000 ELISA: 1:20000. Researchers should empirically determine the suitability of the CATL2 ctsv for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CATL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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